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This study found that the retinol dehydrogenases SDR16C5 and SDR16C6 in mice play a crucial role in skin retinol dehydrogenase activity, affecting hair growth and gland functions without impacting survival.

This study found that protein extracts from human hair demonstrated significant antioxidant abilities, protecting human dermal fibroblasts from oxidative stress, suggesting potential for biomedical applications.

This paper describes the synthesis of (16S,20S)-3β-hydroxy-5α-pregnane-20,16-carbolactam from tigogenin without presenting new experimental results.

In this study, researchers found that a scallop adhesive protein (Sbp9 Δ) forms strong adhesive coatings via disulfide-sticker strategies, which also promote hair regeneration in mouse models by activating Wnt signaling and enhancing angiogenesis, proving more effective than minoxidil for androgenetic alopecia.

This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.

This study found that Ishige sinicola extract increased hair growth and cell proliferation in cultured vibrissa follicles and mice, suggesting potential benefits for treating alopecia through β-catenin activation and 5α-reductase inhibition.

In this laboratory study, Camellia japonica fruit shell extract showed potential to mitigate hair loss by promoting hair cell growth and reducing harmful effects of DHT and oxidative stress.

In this study, a new Finasteride conjugate showed stronger inhibition of 5α-reductase and similar reduction of prostate hyperplasia in rats compared to Finasteride, with potentially improved toxicity.

This study suggests that dutasteride does not present a significant risk to wild fish populations at typical environmental concentrations, but its notable bioaccumulation requires further investigation.

This study reported that Cacumen Platycladi extract significantly reduced hair loss and increased hair density in a 12-week clinical trial, suggesting it may be a safe and effective natural treatment.

This study found that Ageratum conyzoides extract enhanced hair growth in mice and human follicle cells, showing potential for hormonal modulation, pathway activation, and antioxidant protection; however, further clinical studies are needed to confirm efficacy in humans.

LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.

This study conducted an in silico evaluation and found that berberine displayed better binding interactions with the 5α-reductase enzyme and TGF-β2 compared to minoxidil, suggesting its potential as a therapeutic agent for androgenetic alopecia.

Finasteride reduces melanin production in skin cells.

This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.

In this study, the researchers found that Astragalus sinicus extracts improved wound healing, reduced oxidative stress, and activated crucial signaling pathways in dermal papilla cells damaged by dihydrotestosterone, suggesting it may be a promising ingredient for hair loss treatment.

In this study, PMC was identified as a promising plant for nourishing hair, with effective hair growth promotion and 5α-reductase inhibition observed in both laboratory and animal studies for androgenetic alopecia treatment.

This review discusses the relationship between oxidative stress and polycystic ovarian syndrome and reports no new clinical results; the authors emphasize the need for further research into therapeutic strategies.

This review discusses the ethnobotanical uses and phytochemistry of Plumbago zeylanica L., highlighting its potential pharmacological benefits for conditions such as diabetes and cardiovascular disorders, but reports no new experimental findings.

This study demonstrated that combining l-cystine and thiamin in a formulation may protect against UV-induced damage in growth-limited human epidermal keratinocytes in vitro.

In this study, treatment with oral JAK inhibitors was associated with improved disease outcomes in 80.6% of patients with refractory lichen planopilaris over a mean duration of 5 months.

This review discusses the roles of metabolism, reactive oxygen species, intracellular pH, and cell morphology in influencing cell fate decisions during stem cell differentiation but reports no new experimental results.

This article discusses the FDA's decision not to approve 5α-reductase inhibitors for prostate cancer prevention, citing an increase in high-grade tumors but no mortality evidence, and reports no new results.

HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.

This study demonstrated that modified montmorillonites combined with bacterial cellulose enhanced antimicrobial, wound healing, and tissue regenerative activities in a burn mice model, suggesting potential as an artificial skin substitute for burn patients.

This study found that treatment with oral tofacitinib, alone or with other therapies, was associated with clinical improvement in most patients with recalcitrant lichen planopilaris.

This review discusses the impact of air pollution on skin health and suggests that targeting oxidative stress products like HNE could be a new strategy for treating related skin conditions.

This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.

This study identified new genes and compounds affecting hair cell survival during ototoxin exposure using the zebrafish model, potentially aiding in understanding and preventing hearing loss and balance disorders in humans.

This study found that ionizing radiation primarily affects keratinocyte stem cells in the hair follicle, suggesting they play a central role in radiation-induced hair graying, rather than melanocyte stem cells.