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Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Hair loss may increase heart disease risk.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Using tamsulosin and finasteride together for benign prostatic syndrome has increased and shows improvement in symptoms, but more reliable comparisons are needed.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Minoxidil with caffeine works better for hair loss than minoxidil alone.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Dutasteride effectively treats benign prostatic hyperplasia, improving symptoms and quality of life.

Muscles can make their own androgens, which may help muscle growth.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Dutasteride may help shrink prostate cancer tumors.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

A new compound effectively inhibits human 5α-reductase 1.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.