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    Research 181–210 of 1000+

    1. Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1 Bioorganic & Medicinal Chemistry · 2001 · 12 citations
    2. Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity Endocrine journal · 1998 · 12 citations
    3. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    4. Metabolic dysfunction in female mice with disruption of 5α-reductase 1 2017 · 11 citations
    5. Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days The Journal of Urology · 2010 · 11 citations
    6. Anti-nociceptive and anti-inflammatory properties of 5alpha-reductase inhibitor finasteride in experimental animals European Journal of Drug Metabolism and Pharmacokinetics · 2008 · 11 citations
    7. 5α-Reductase and 11β-Hydroxysteroid Dehydrogenase Activity in Prepubertal Hispanic Girls with Premature Adrenarche The Journal of Clinical Endocrinology & Metabolism · 2002 · 11 citations
    8. Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia Archives of Dermatology · 1997 · 11 citations
    9. Is there a role for 5α‐reductase inhibitors in transgender individuals? International Journal of Andrology · 2020 · 10 citations
    10. Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage—Animal, Experimental Study International Journal of Environmental Research and Public Health · 2019 · 10 citations
    11. Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · 10 citations
    12. Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride International Journal of Andrology · 2010 · 10 citations
    13. Enzyme-linked immunosorbent assays for doping control of 5α-reductase inhibitors finasteride and dutasteride Analytica Chimica Acta · 2010 · 10 citations
    14. Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche. Journal of Investigative Dermatology · 1998 · 10 citations
    15. Greater conversion of testosterone to 5α-dihydrotestosterone, reflecting increased peripheral 5α-reductase activity in nude mice treated with high doses of cyclosporine A Journal of Steroid Biochemistry · 1990 · 10 citations
    16. COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE? Endocrinology · 1991 · 9 citations
    17. Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing BMC Biology · 2022 · 8 citations
    18. The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder Journal of Clinical Investigation · 2021 · 8 citations
    19. Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids The Journal of Clinical Endocrinology and Metabolism · 2020 · 8 citations
    20. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    21. Comparative GC-MS Based In vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction Mass spectrometry letters · 2012 · 8 citations
    22. 5α-Reductase, an enzyme regulating glucocorticoid action in the testis of Rhinella arenarum (Amphibia: Anura) General and Comparative Endocrinology · 2012 · 8 citations
    23. Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2 Archiv Der Pharmazie · 2002 · 8 citations
    24. Proscar@ (Finasteride) inhibits 5α-reductase activity in the ovaries and testes of Lytechinus variegatus Lamarck (Echinodermata: Echinoidea) Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology · 1998 · 8 citations
    25. Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase Helvetica Chimica Acta · 1995 · 8 citations
    26. 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency European Urology · 1991 · 8 citations
    27. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects Pharmaceuticals · 2022 · 7 citations
    28. Screening of Euphorbiaceae Plant Extracts for Anti-5α-reductase Biological & Pharmaceutical Bulletin · 2018 · 7 citations
    29. Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions Journal of Functional Biomaterials · 2018 · 7 citations
    30. Inhibition of 5α-reductase alters pregnane metabolism in the late pregnant mare Reproduction · 2018 · 7 citations