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    Research 421–450 of 1000+

    1. Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review Expert opinion on therapeutic patents · 2017 · 70 citations
    2. Finasteride: A slow-binding 5.alpha.-reductase inhibitor Biochemistry · 1993 · 70 citations
    3. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-<i>α</i>-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002 · 68 citations
    4. Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta) Teratology · 1997 · 67 citations
    5. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-<i>α</i>-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002 · 65 citations
    6. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. The Journal of Clinical Endocrinology and Metabolism · 1994 · 59 citations
    7. The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency. The Journal of Clinical Endocrinology & Metabolism · 1995 · 54 citations
    8. 5 alpha-reductase-2 gene mutations in the Dominican Republic. The Journal of Clinical Endocrinology & Metabolism · 1996 · 53 citations
    9. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    10. Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Re-growth in Testosterone-treated Mice Phytotherapy Research · 2011 · 51 citations
    11. The effect of spironolactone on genital skin 5α-reductase activity 1985 · 50 citations
    12. Selective non-steroidal inhibitors of 5α-reductase type 1 2004 · 49 citations
    13. Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex Journal of Biological Chemistry · 2009 · 47 citations
    14. 5 Alpha-reductase inhibitors: whatʼs new? Current opinion in urology · 2003 · 47 citations
    15. Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss Journal of The American Academy of Dermatology · 1999 · 46 citations
    16. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride Hormone Molecular Biology and Clinical Investigation · 2010 · 45 citations
    17. 5-α-Reductase inhibitors for prostate cancer chemoprevention: an updated Cochrane systematic review BJUI · 2010 · 44 citations
    18. Testosterone 5.ALPHA.-Reductase Inhibitory Active Constituents of Piper nigrum Leaf Biological & pharmaceutical bulletin · 2007 · 44 citations
    19. 5-α-Reductase type 2 deficiency: is there a genotype-phenotype correlation? A review Hormones · 2018 · 39 citations
    20. Reduced levels of 5-α reductase 2 in adult prostate tissue and implications for BPH therapy 2011 · 39 citations
    21. 5-Alpha reductase deficiency Current Opinion in Endocrinology, Diabetes and Obesity · 2014 · 38 citations
    22. Anti-androgenic and Hair Growth Promoting Activities of Lygodii Spora (Spore of Lygodium japonicum) I. Active Constituents Inhibiting Testosterone 5.ALPHA.-Reductase. Biological & Pharmaceutical Bulletin · 2002 · 38 citations
    23. Five-alpha-reductase Inhibitors for prostate cancer prevention. The Cochrane library · 2008 · 37 citations
    24. The long-term effect of specific type II 5alpha-reductase inhibition with finasteride on bone mineral density in men: results of a 4-year placebo controlled trial. PubMed · 2002 · 37 citations
    25. 5‐alpha‐reductase inhibitors are associated with reduced frequency of COVID‐19 symptoms in males with androgenetic alopecia Journal of The European Academy of Dermatology and Venereology · 2020 · 36 citations
    26. A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome Urology · 2018 · 35 citations
    27. Side Effects of 5‐Alpha Reductase Inhibitors: A Comprehensive Review Sexual medicine reviews · 2013 · 35 citations
    28. Sex dependent influence of a functional polymorphism in steroid 5‐α‐reductase type 2 (<i>SRD5A2</i>) on post‐traumatic stress symptoms American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2013 · 35 citations
    29. Inhibitory activities of Puerariae Flos against testosterone 5α-reductase and its hair growth promotion activities Journal of Natural Medicines · 2011 · 34 citations
    30. Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin 1993 · 34 citations