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Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Prolactin affects when mice shed and grow hair.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Finasteride doesn't negatively affect sexual function in Indian men with hair loss.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Hair loss drugs may cause sexual issues and infertility in men.

DHT, a testosterone byproduct, causes male pattern baldness.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

PFS might be a delusional disorder with potential to become mass psychogenic illness.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

5ARI treatment improves hair growth in older men with minimal side effects.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Cyproterone acetate reduced hair growth in most hirsute females and made hair softer, thinner, and lighter.

Finasteride helps female-pattern hair loss.

Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

New genes and pathways are important for testosterone production and male sexual development.