research Testosterone Metabolite Nonessential For Androgen Effects
The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
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research Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year
Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
research Finasteride
Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
research Finasteride, 1 Mg Daily Administration on Male Androgenetic Alopecia in Different Age Groups: 10-Year Follow-Up
Finasteride effectively increases hair growth in men with AGA, works better for those over 30, and may cause some side effects.
research Maximum Efficacy of Finasteride Is Obtained Within 6 Months and Maintained Over 6 Years
Finasteride works best in 6 months and lasts 6 years.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome
Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
research Dutasteride Reduces Alcohol’s Sedative Effects in Men in a Human Laboratory Setting and Reduces Drinking in the Natural Environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
research 5-Alpha Reductase Inhibitors in Androgenetic Alopecia: Shifting Paradigms, Current Concepts, Comparative Efficacy, and Safety
Dutasteride works better than finasteride for hair loss, with both being safe to use.
research Progranulin, A Secreted Tumorigenesis And Dementia-Related Factor, Regulates Mouse Hair Growth
Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.
research Implications of Neuroimaging for the Treatment of Epilepsy
Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
research Slow Progress in Prostate Cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
research Aging of the Hair Follicle Pigmentation System
Hair grays due to oxidative stress and fewer functioning melanocytes.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research Desferrioxamine Treatment of Aceruloplasminemia: Long-Term Follow-Up
Finasteride may help reduce symptoms in male Tourette syndrome patients.
research Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats
Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
research Increased Insulin Sensitivity by Metformin Enhances Intense-Pulsed-Light-Assisted Hair Removal in Patients with Polycystic Ovary Syndrome
Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
research Reproductive Outcomes of Female Patients with Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency
Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.
research Encephalitis Lethargica Due to Epstein–Barr Virus Infection
Finasteride may help reduce tic severity in male Tourette syndrome patients.
research WS PRO 160 I 120 mg (A Combination of Sabal and Urtica Extract) in Patients with LUTS Related to BPH
WS PRO 160 I 120 mg effectively treats urinary symptoms from BPH with good safety and tolerability.
research Abstracts from the 17th Congress of the European Society for Dermatology and Psychiatry
The congress showed that psychological therapy can help skin condition patients, social media affects acne stigma, education improves atopic dermatitis, and patient satisfaction in dermatology is high, especially with good doctor engagement.
research Usefulness of the Vasodilator Minoxidil in Resistant Hypertension
Minoxidil effectively lowers blood pressure in patients with resistant hypertension.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research Function and Underlying Mechanisms of Seasonal Color Molting in Mammals and Birds: What Keeps Them Changing in a Warming World?
Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
research A PAX1 Enhancer Locus Is Associated With Susceptibility to Idiopathic Scoliosis in Females
A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
research Male Pattern Hair Loss: Current Understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research Acneiform Dermatoses
Some skin conditions look like acne but are caused by drugs, and they usually get better when the drug is stopped.
research Protective Effects of Melatonin Against Metabolic and Reproductive Disturbances in Polycystic Ovary Syndrome in Rats
Melatonin may help treat PCOS symptoms in rats.
research Clinical Features of Familial Lewy Body Parkinsonism Caused by α-Synuclein Triplication (Iowa Kindred) with Video Documentation
The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.