research Position Effect on FGF13 Associated with X-Linked Congenital Generalized Hypertrichosis
FGF13 gene changes cause excessive hair growth in a rare condition.
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630-660 / 1000+ resultsresearch Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research Female Pattern Alopecia: Current Perspectives
Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
research Inhibition of Wnt/β-Catenin Pathway Promotes Regenerative Repair of Cutaneous and Cartilage Injury
Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
research SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice
SIRT7 protein is crucial for starting hair growth in mice.
research Identification of Sirtuin 1 as a Promising Therapeutic Target for Hypertrophic Scars
Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
research Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands
Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
research Effect of P144 (Anti-TGF-β) in an In Vivo Human Hypertrophic Scar Model in Nude Mice
P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.
research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research Autofluorescence in the Stem Cell Region of the Hair Follicle Bulge
Autofluorescence in hair follicle stem cells can interfere with studies but may help isolate these cells.
research Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells
Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.
research PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair
PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
research Optimization of Lipid-Based Nanoformulation for Cutaneous Targeting: Niosomes as Potential Candidates
Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.
research Off-Label Use of Botulinum Toxin in Dermatology: Current State of the Art
Botulinum toxin is effective for various skin conditions, but more research and awareness of side effects are needed.
research Anti-Wrinkle Effect of Bone Morphogenetic Protein Receptor 1a Extracellular Domain (BMPR1a-ECD)
BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
research Alleviation of Androgenetic Alopecia with Aqueous Paeonia Lactiflora and Poria Cocos Extract Intake Through Suppressing the Steroid Hormone and Inflammatory Pathway
Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.
research Single Cell Analysis of Transcriptome and Open Chromatin Reveals the Dynamics of Hair Follicle Stem Cell Aging
Hair follicle stem cells change states with age, affecting hair growth and aging.
research Hair for Brain Trade-Off: A Metabolic Bypass for Encephalization
Human hair loss may have evolved to help increase brain size.
research AIRE Deficiency Leads to the Development of Alopecia Areata-Like Lesions in Mice
AIRE deficiency causes hair loss similar to alopecia areata in mice.
research Blue Laser Irradiation Decreases ATP Levels in Mouse Skin and Increases Production of Superoxide Anion and Hypochlorous Acid in Mouse Fibroblasts
Blue laser light reduces energy in mouse skin cells and creates harmful oxygen compounds, possibly harming the cells.
research Topical Delivery of Tofacitinib in Dermatology: The Promise of a Novel Therapeutic Class Using Biodegradable Dendritic Polyglycerol Sulfates
A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.
research Fibronectin Connecting Cell Sheet Based on Click Chemistry for Wound Repair
Fibronectin-attached cell sheets improve wound healing and are safe and effective.
research Melatonin Protects K15+ Human Hair Follicle Stem Cells and Hair Matrix Keratinocytes Against Paclitaxel-Induced Damage Ex Vivo
Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.
research Temporary Cell Cycle Arrest in Human Scalp Hair Follicles and Their Epithelial Stem Cells by ALRN-6924: A Novel Strategy to Selectively Protect p53-Wildtype Cells Against Paclitaxel-Induced Alopecia
ALRN-6924 may prevent hair loss caused by chemotherapy.
research Refractory Pruritic Fox-Fordyce Disease Successfully Treated With Botulinum Toxin Type A
Botox injections may be a safe and effective way to treat severe, itchy skin disease when other treatments fail.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Use of the Drug Wolvit (Biotin 5 mg) in Treatment of Diffuse Telogen Alopecia
Wolvit® (biotin 5 mg) is effective and safe for treating hair loss and scalp conditions in women.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
research Revealing Novel Insights on How Oral Supplementation With Collagen Peptides May Prevent Hair Loss: Lessons From the Human Hair Follicle Organ Culture
Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.