23 citations
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September 2011 in “Journal of Dermatological Science” This study explored the effects of a new narrow-band red LED light on hair growth in mice, showing potential benefits compared to existing laser therapies.
August 2019 in “Research Square (Research Square)” This study found that exposure to red LED light may improve fibre quality and hair follicle development in Angora rabbits, potentially due to increased melatonin secretion.
October 2024 in “Photodermatology Photoimmunology & Photomedicine” In this study, participants with androgenetic alopecia who used an LED helmet emitting red and green light experienced significant improvements in hair growth measures, with red light showing superior results in increasing hair diameter and reducing vellus hair density over 6 months.
January 2024 in “Annals of Agricultural and Environmental Medicine” This study observed that LED therapy improved hair regrowth and reduced hair loss in patients with post-COVID telogen effluvium, with or without androgenetic alopecia, compared to those who did not receive LED treatment.
117 citations
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September 2013 in “Lasers in Surgery and Medicine” This study found that low level laser therapy at 655 nm significantly increased hair counts in males with androgenetic alopecia.
19 citations
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February 2018 in “Lasers in Medical Science” This study found that 655-nm red light with LED enhanced hair shaft elongation and reduced catagen transition in human hair follicles in vitro by activating the Wnt/ß-catenin signaling pathway.
81 citations
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August 2014 in “Lasers in Surgery and Medicine” This study found that low-level laser therapy significantly increased hair growth in women with androgenic alopecia, achieving a 37% greater increase in hair counts compared to placebo.
January 2026 in “Journal of Hard Tissue Biology” This study found that red LED photobiomodulation significantly enhanced both the metabolic activity and proliferation of human placenta-derived pericytes, alongside increased expression of angiogenic markers, suggesting a potential non-invasive approach to aid tissue repair and vascular regeneration.
August 2025 in “Photodermatology Photoimmunology & Photomedicine” This review found that LED therapy, using light in specific wavelengths, may offer effective, non-invasive treatment options for various skin conditions, including acne, melasma, photoaging, and wound healing.
February 2023 in “Cosmoderma” This study found that combining red light therapy with oral beta-carotene significantly improved photoaging treatment outcomes compared to red light therapy alone, with Group A showing a 56.12% reduction in photoaging scores over 12 weeks versus 44.78% in Group B.
62 citations
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July 2018 in “Lasers in Medical Science” In this review, the researchers highlight LED therapy as an emerging and safe treatment for skin inflammatory conditions, aging, and hair growth disorders, noting its integration into dermatological practice but emphasizing the need for more controlled studies to confirm its efficacy.
8 citations
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November 2020 in “Optics and Laser Technology” This review discusses the applications and advantages of LED-based photobiomodulation therapy for dermatological and cosmetic purposes but highlights existing challenges and health concerns while exploring future perspectives.
2 citations
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December 2024 in “Journal of Photochemistry and Photobiology B Biology” This study suggests that pulsed wave photobiomodulation could be a promising treatment for androgenetic alopecia by enhancing dermal papilla cell function through specific light parameters, particularly frequency.
September 2024 in “Archives of Dermatological Research” This study found that both red and green LED therapies combined with a microneedling patch significantly improved hair density and diameter in androgenetic alopecia patients over 24 weeks, with no serious side effects and similar efficacy between the two light wavelengths.
November 2025 in “Revista Multidisciplinar do Nordeste Mineiro” This study's review of existing literature suggests potential benefits of red LED photobiomodulation for treating telogen effluvium, but highlights a lack of standardized parameters and calls for further controlled trials.
January 2026 in “Forum Dermatologicum” This review concluded that LED-based photobiomodulation is generally safe and effective for certain dermatologic conditions, though consumer devices often show less efficacy compared to professional systems.
This article reviews low-level light therapy for various types of hair loss and reports no new clinical results; the authors note its safety and advantages but lack data on individual treatment response.
41 citations
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October 2024 in “Nature Communications” In this study, researchers developed a wearable red and blue LED patch and a sprayable fibrin gel to treat infected wounds at home, demonstrating effective infection control and enhanced wound healing in diabetic mice and minipigs.
5 citations
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October 2023 in “International Wound Journal” In this study, a novel portable LED device significantly accelerated wound healing in rats, with faster wound closure, increased collagen deposition, and more microvessels at a higher radiation intensity, suggesting its potential for innovative wound management.
14 citations
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November 2022 in “Archives of Dermatological Research” This study found that a green-light LED microneedle patch enhanced hair growth in mice with the best results among tested wavelengths, showing increased hair follicles and no serious side effects, suggesting its potential for treating androgenetic alopecia.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and move by activating certain cell pathways.
January 2016 in “프로그램북(구 초록집)” In this study, LED irradiation was found to promote hORSC proliferation and stimulate the Wnt5a/β-catenin and ERK signaling pathways, suggesting a potential mechanism for hair growth.
January 2026 in “American Journal of Medical and Clinical Research & Reviews” The study discusses using red light therapy for hair regrowth, noting red light alone may aid non-inflammatory hair loss, while infrared-red light combination is necessary for conditions like alopecia areata.
1 citations
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November 2021 in “IntechOpen eBooks” This review covers red light Transcranial LED therapy for hippocampal memory impairment in aging and Alzheimer's but reports no clinical results, highlighting a need for further research into its mechanisms and effects.
April 2021 in “Institutional Repositories DataBase (IRDB)” This study reported that high-intensity red LED irradiation increased osteogenic differentiation and mineralization of human bone marrow mesenchymal stem cells, potentially through Wnt/β-catenin pathway activation.
Among participants in a 26-week trial, this study by REVIAN Inc. reported that their REVIAN RED dual wavelength LED light treatment for androgenetic alopecia was both safe and effective at the 16-week mark.
June 2025 in “Journal of Education Health and Sport” This review highlights that while finasteride and minoxidil effectively treat androgenetic alopecia, emerging options like dutasteride, mesotherapy, androgen blockers, and red LED therapy show promising results, especially when used in combination, though further research is needed for standardization and safety confirmation.
December 2024 in “Journal of Biophotonics” In this study, researchers observed that red and red-orange LED light therapy stimulates nitric oxide production and decreases dihydrotestosterone synthesis in cell models, suggesting a potential mechanism for using light therapy to treat androgenetic alopecia.
2 citations
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May 2023 in “Photobiomodulation, photomedicine, and laser surgery” This editorial reviews how photobiomodulation therapy might effectively treat both hyperpigmentation and depigmentation skin disorders, but reports no new clinical results.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.