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Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.

Intermittent fasting slows hair growth by damaging hair follicle cells.

Dermal papilla cells can help regrow hair and are promising for hair loss treatments.

miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.

Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.

Ovarian drilling surgery is not clearly better than medical treatments for PCOS symptoms.

Spirulina extract and C-phycocyanin may help heal wounds.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.