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Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Androgens slow hair growth by altering Wnt signaling in balding cells.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

Nonionic liposomes are the best for delivering genes to skin cells.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.