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Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.

Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

MSC-protein helps regenerate gum tissue and bone.

Blocking JAK-STAT signaling can lead to hair growth.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Both mouse and rat models are effective for testing alopecia areata treatments.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Thymosin β4 helps improve skin healing and reduce scarring.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

The anti-CXCL4 antibody helps mice grow hair faster and prevents hair loss.

Nerve growth factor helps cashmere goat hair cells grow by activating a specific protein.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.

COVID-19 can cause temporary hair loss, which is commonly reversible with treatment.

FGF12 is important for hair growth and could be targeted for hair loss treatment.

A synthetic octapeptide may help promote hair growth and counteract hair loss.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.