36 citations,
April 2018 in “Journal of Investigative Dermatology” Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
36 citations,
December 2015 in “Drugs” New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
36 citations,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
32 citations,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
32 citations,
March 2015 in “The Journal of Clinical Endocrinology & Metabolism” Alopecia areata is linked to thyroid autoimmunity but not type 1 diabetes.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
31 citations,
June 2017 in “Regeneration” BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.
28 citations,
December 2012 in “The American Journal of Cosmetic Surgery” Proteins from stem cells improved hair growth in patients with hair loss.
27 citations,
January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
25 citations,
June 2021 in “Developmental Cell” Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
24 citations,
June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
24 citations,
January 2012 in “Journal of Cellular Biochemistry” C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.
23 citations,
June 2015 in “Clinica Chimica Acta” Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.
23 citations,
January 2014 in “Molecular Therapy” Applying a special DNA plasmid to the skin can make it thicker and stronger.
23 citations,
January 2014 in “International Journal of Biological Sciences” African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.
21 citations,
August 2003 in “Seminars in oncology nursing” Nurses are crucial in managing chemotherapy side effects for ovarian cancer patients to improve their quality of life.
20 citations,
September 2021 in “Nature communications” Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
20 citations,
October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
20 citations,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
20 citations,
January 2012 in “Journal of Steroids & Hormonal Science” The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
20 citations,
September 2006 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” New drugs are improving treatment for hormone-related diseases in small pets.
19 citations,
May 2016 in “Clinical, cosmetic and investigational dermatology” FGF-2&D/P nanoparticles can help treat hair loss.
19 citations,
November 2011 Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
19 citations,
January 2011 in “Obstetrics and gynecology international” Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.
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October 1994 in “Tumori Journal” As of 1994, treatments for liver cancer had not significantly improved patient survival.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
18 citations,
August 2015 in “Biochemical and Biophysical Research Communications” XEDAR triggers a specific signaling pathway in cells.
18 citations,
March 2015 in “Journal of Endocrinological Investigation” The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.