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Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

The conclusion is that maintaining blinding in clinical trials is crucial for reliable results.

Troglitazone increases subcutaneous fat in lipodystrophy patients.

The document concludes that there is no credible evidence that distant healing works, and it should not be further studied in medical literature.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Pimpinella anisum L. extract significantly boosts hair growth in mice.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

The anti-CXCL4 antibody helps mice grow hair faster and prevents hair loss.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Gene mutations can cause problems in male genital development.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

New cancer treatments are more precise and less toxic, improving survival rates, but Asia faces challenges in adopting these advancements.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.

Antibody treatments show promise for hair loss but need more research.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

Different treatments for PCOS should be tailored to the individual, including lifestyle changes and various medications.

Fermented soy protein may help prevent bone loss by affecting bone cell activity.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.