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Human skin can make serotonin and melatonin, which help protect and maintain it.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Fat cells help recruit healing cells and build skin structure during wound healing.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Noggin is necessary to start the hair growth phase in skin after birth.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.