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Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Selective breeding can enhance immunity in dairy cattle.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.

Flavonoids and Nod factors are key for legume plant growth and could help in sustainable farming.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Sorafenib causes skin reactions by increasing the number and activity of skin mast cells.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Muscles can make their own androgens, which may help muscle growth.

Blocking certain immune signals can reduce skin damage from radiation therapy.