research Steroid Hormones: Overview and Medical Applications
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
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research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research Endocrinology, Brain, and Pituitary Gland
Hormones control reproduction and are crucial for body balance.
research Androgen Regulation of a Specific Gene in Hamster Flank Organs
Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research Men With Kennedy Disease Have a Reduced Risk of Androgenetic Alopecia
Men with Kennedy disease have less chance of hair loss.
research Functional Enhancers as Master Regulators of Tissue-Specific Gene Regulation and Cancer Development
Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance
T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
research Dihydrotestosterone Induces Arterial Stiffening in Female Mice
Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
research A Homozygous Missense Mutation in the Fibroblast Growth Factor 5 Gene Is Associated with the Long-Hair Trait in Angora Rabbits
A specific gene mutation causes long hair in Angora rabbits.
research Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research FGF5 Is a Crucial Regulator of Hair Length in Humans
FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations
Deleting MED1 in skin cells causes hair loss and skin changes.
research TGFβ and Cancer Metastasis: An Inflammation Link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Ethinylestradiol/Chlormadinone Acetate: Benefits and Efficacy
Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.
research Cutaneous Transcriptome Analysis in NIH Hairless Mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles
Caffeine may help reduce stress-induced hair loss.
research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Mechanism of Action of Bolandiol (19-Nortestosterone-3β,17β-Diol), a Unique Anabolic Steroid with Androgenic, Estrogenic, and Progestational Activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Androgens, like DHT, affect hair growth and treatments like finasteride may help.
research Australasian Society for Dermatology Research Meeting, May 2006
The meeting highlighted the genetic basis of female pattern hair loss and various skin health insights.
research Hormonal Parameters in Androgenetic Hair Loss in Males
Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.
research Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp
Cells from balding scalps have more androgen receptors than cells from non-balding scalps.