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Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Dutasteride and finasteride affect different cell types differently.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

RANK-RANKL signaling is essential for hair growth and skin health.

Alopecia areata involves specific T-cells, unlike androgenetic alopecia.

No clear link between androgen receptor variation and hair loss, but more research needed.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Activating TRPV3 stops human hair growth.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Prolactin affects when mice shed and grow hair.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Certain essential oils can activate a human skin receptor, potentially helping with skin disorders.

Certain gene variations are not a major cause of male infertility in Nigerian men.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.