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PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Combining cosmetic procedures with lifestyle changes improves antiaging results.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Cannabinoids may help treat various skin conditions.

Antioxidants might help prevent pressure ulcers, but more research is needed to find effective ones.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

TLR4 is important in aging-related diseases and could be a new treatment target.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.

Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.

PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.

Exosomal miRNAs from stem cells can help improve skin health and delay aging.

Light therapy on the brain shows promise for treating brain diseases and improving brain function.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Enzymes called PADIs play a key role in hair growth and loss.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Activating Nrf2 can help protect against hearing loss.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.