research The Microbiome in Patients with Atopic Dermatitis
People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
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810-840 / 1000+ resultsresearch Polycystic Ovary Syndrome (PCOS): An Inflammatory, Systemic, Lifestyle Endocrinopathy
PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
research The Selective Androgen Receptor Modulator GTx-024 (Enobosarm) Improves Lean Body Mass and Physical Function in Healthy Elderly Men and Postmenopausal Women: Results of a Double-Blind, Placebo-Controlled Phase II Trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack
Hair follicles prevent NK cell attacks to avoid hair loss.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research Host-Microbiome Interactions and Recent Progress in Understanding the Biology of Acne Vulgaris
Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.
research Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier
Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism
Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
research The Fate of Trichohyalin
Trichohyalin is modified by enzymes to form strong structures in hair cells.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research Disturbance of the Circadian System in Shift Work and Its Health Impact
Shift work disrupts the body's natural clock, leading to health problems.
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents
Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Evolution of Hard Proteins in the Sauropsid Integument in Relation to the Cornification of Skin Derivatives in Amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
research A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle
A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
research Types of Hair Dye and Their Mechanisms of Action
Hair dyes vary in how long they last and how deeply they penetrate hair.
research Pharmacologic Interventions in Aging Hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Cutaneous Permeation And Penetration Of Sunscreens: Formulation Strategies And In Vitro Methods
Effective sunscreen formulations can reduce skin absorption and enhance protection.
research Heavily Hunted Wolves Have Higher Stress and Reproductive Steroids Than Wolves With Lower Hunting Pressure
Heavily hunted wolves have higher stress and reproductive hormone levels.
research Hydrogen Sulfide Disturbs Actin Polymerization via S-Sulfhydration Resulting in Stunted Root Hair Growth
Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.
research An Overview of Chemical Straightening of Human Hair: Technical Aspects, Potential Risks to Hair Fiber and Health, and Legal Issues
Chemical hair straightening can damage hair and health, needing safer alternatives and stricter regulations.
research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
research Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions
Stress hormones and autoimmune reactions can cause hair loss.
research Recent Advances in the Structural Design of Photosensitive Agent Formulations Using Soft Colloidal Nanocarriers
New nanocarriers improve drug delivery for disease treatment.
research Specific Morphogenetic Events in Mouse External Genitalia Sex Differentiation Are Dependent Upon Androgens and Estrogens
Mouse genital development depends on male or female hormones for specific features.