research Antioxidants and Lipid Peroxidation Status in the Blood of Patients with Alopecia
Alopecia patients have lower antioxidants and higher lipid damage in their blood.
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research An Investigation of Vitamin D Status in Alopecia Areata
People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.
research Evaluation of Cardiovascular Disease Risk Factors in Patients with Mycosis Fungoides
Patients with mycosis fungoides have a higher risk of heart disease.
research Impact of Lisinopril on Cardiometabolic Risk Factors in Men with Hypertension and Early-Onset Androgenetic Alopecia
Lisinopril improves heart health more in men with normal hair than those with early hair loss.
research Anabolic-Androgenic Steroids and Cardiometabolic Derangements
Long-term anabolic steroid use can lead to heart and metabolic health issues.
research Selenium and Systemic Lupus Erythematosus (SLE): A Double-Blind Randomized Controlled Trial
Selenium supplements can help improve symptoms and metabolic markers in lupus patients.
research Evaluation of Biochemical and Hematological Parameters in Polycystic Ovarian Syndrome Among Urban College Girls
Polycystic Ovarian Syndrome is common in overweight urban college girls and may increase the risk of heart and metabolic problems.
research Lab Quality Management and Methodology
Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
research Activation of Astrocytes In Vitro by Macrophages Polarized with Keratin Biomaterial Treatment
Keratin treatment reduces astrocyte reactivity and inflammation.
research Revisiting Dandruff: Role of Malassezia Yeasts and Treatment Implications
Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
research Fullerene C60 with Cytoprotective and Cytotoxic Potential: Prospects as a Novel Treatment Agent in Dermatology
Fullerene C60 shows promise as a new treatment for various skin conditions.
research Factors Associated with Anti-SARS-CoV-2 IgG Antibody Production in Patients Convalescing from COVID-19
Men, diabetes, and high inflammation levels lead to higher COVID-19 antibodies.
research Birth, Life, and Death of the MAGE3 Hypothesis of Alopecia Areata Pathobiology
The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.
research Mitochondrial DNA Damage, Oxidative Stress, And Atherosclerosis
Improving mitochondrial health may better treat atherosclerosis than antioxidants.
research Aromatic C-Nitrosation of a Bioactive Molecule: Nitrosation of Minoxidil
Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.
research Castleman's Disease Combined with the Development of Systemic Lupus Erythematosus
A 16-year-old boy with Castleman's disease and lupus was successfully treated and showed no recurrence.
research Cardiometabolic Risk Factors in Women with Non-Classic Congenital Adrenal Hyperplasia
Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.
research Bullous Pyoderma Gangrenosum Occurring on a Cesarean Section Scar
Bullous pyoderma gangrenosum can develop on cesarean scars and may require steroids for treatment.
research The Effect of Low-Level Laser Therapy on Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cells
Low-level laser therapy may help uninfected cells but has different effects on coronavirus-infected cells.
research Defining Trichoscopy Clues in Children with Alopecia Areata
Trichoscopy is essential for diagnosing and managing alopecia areata in children.
research The Molecular Link Between Auxin and ROS-Mediated Polar Root Hair Growth
Plant root hair growth is controlled by the hormone auxin, which affects the production of certain oxygen-related molecules through a specific process.
research Verrucous Hemangioma Leg: A Challenging Birthmark
A boy with a rare birthmark called verrucous hemangioma needed careful timing for surgery due to its size and depth.
research Somatosensory Organization and Behavior in Naked Mole-Rats: Peripheral Structures, Innervation, and Selective Lack of Neuropeptides Associated with Thermoregulation and Pain
Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.
research Hair Disorders in Patients with Cancer
Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.
research Ameliorative Effects of Rutin Against Metabolic, Biochemical, and Hormonal Disturbances in Polycystic Ovary Syndrome in Rats
Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis
Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.
research Using the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell death
The study used zebrafish to investigate drug-induced hair cell death and identify protective agents. Zebrafish were ideal due to their genetic similarities to mammals and external hair cells. Researchers found three zebrafish mutants resistant to neomycin-induced hair cell death, involving genes not previously linked to hair cell toxicity. They screened 10,960 compounds, identifying several protective agents, including FDA-approved drugs. The study revealed that many protective compounds did not affect the bactericidal activity of aminoglycosides, except Benzamil. Selective estrogen receptor modulators were effective against neomycin exposure. The research highlighted disrupted calcium homeostasis as a mechanism of hair cell toxicity, with calcium release from the endoplasmic reticulum causing mitochondrial dysfunction and increased reactive oxygen species. The zebrafish model was effective in understanding hair cell death mechanisms and identifying potential treatments for hearing loss and balance disorders.
research Peripheral Arterial Disease: Diagnosis and Management
Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.
research Quaternary Ammonium Iminofullerenes Improve Root Growth of Oxidative-Stress Maize Through ASA-GSH Cycle Modulating Redox Homeostasis of Roots and ROS-Mediated Root-Hair Elongation
Quaternary ammonium iminofullerenes help maize roots grow better under stress by reducing oxidative damage.