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Mice can regenerate ear tissue without the p53 protein.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.

Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Hair growth environment recreated with challenges; stem cells make successful skin organoids.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.

Concentrated nanofat helps mice grow hair by activating skin cells and may be used to treat hair loss.

Gray hair can potentially be reversed, leading to new treatments.

Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.

Some skin conditions may increase the risk of heart disease, but are not yet included in cardiovascular prevention guidelines.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.

Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.

Targeted immunotherapy could be a promising new treatment for hair regrowth.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.

Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.

The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.