Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identifies a polygenic basis for atypical recurrent flank alopecia in Cesky Fousek dogs through genome-wide association analysis and gene expression profiling, highlighting several metabolic pathways involved in the condition.

In this study, the use of rb‐bFGF in hair transplantation significantly increased follicle survival, reduced hair loss, improved patient satisfaction, and decreased complications compared to controls, in patients with androgenetic alopecia over a 12-month period.

This study found that HPV16 oncogene expression in multipotent epithelial stem cells led to abnormal mobilization, altering their quiescence without affecting other stem cell markers, suggesting a distinct stem cell compartment.

This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.

This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.

This study found that specific ATP-competitive TOR inhibitors (asTORis) decrease root growth in Arabidopsis thaliana in a dose-dependent manner, similar to their effects on mammalian cells.

This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.

This review updates the understanding of fibroblast heterogeneity in wound healing, discussing advancements in fibroblast roles and potential therapies, but it reports no new clinical results.

This study found that epidermal growth factor significantly enhances the proliferation of hair follicle-derived mesenchymal stem cells through the EGFR/ERK and AKT pathways, without involving the STAT3 pathway.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

This abstract omits specific findings and does not provide new research results.

This study found that sweat gland stem cells primarily maintain sweat gland homeostasis but can trans-differentiate to aid in epidermal healing and regenerate diverse skin structures under certain conditions.

This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.

This review discusses the pathophysiology, genetics, and management of nonclassic congenital adrenal hyperplasia, noting subfertility and hormonal issues without providing new clinical results.

This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.

This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.

This study observed significant differences in immune cell infiltration and gene expression across different skin sites, with the back displaying higher tolerance-promoting immune mechanisms, which may enhance epicutaneous immunotherapy outcomes.

This review discusses recent findings on molecular changes in cutaneous adnexal tumours and reports novel markers and pathways involved, highlighting the diverse oncogenic drivers and tumour suppressor alterations.

This study found that activating CB1 receptor signaling in human hair follicles increased stem cell proliferation while reducing differentiated cell survival, suggesting CB1's role as a survival stimulus for epithelial stem cells.

This study found that UVB irradiation alters skin stem cell niches leading to signs of photoaging, which may be reversed by adipose-derived stem cells through BMP4 pathway modulation and niche remodeling.

This review discusses the potential of follicular drug delivery systems to target the pilosebaceous unit and reports no new research findings.

This study found that Wnt10b promotes the proliferation of hair follicle stem cells and hair precortex cells, revealing them as target cells in Wnt10b-induced hair follicle regeneration.

This review explores the molecular processes behind hair follicle stem cell activation and suggests new potential targets for designing therapies for various types of alopecia, but it reports no clinical results.

This study found that 5-bromo-3,4-dihydroxybenzaldehyde (BDB) promoted hair growth in rat vibrissa follicles by activating Wnt/β-catenin and autophagy pathways and inhibiting the TGF-β pathway in dermal papilla cells.

This study found that low-frequency sonophoresis significantly decreased the skin penetration of sodium fluorescein-loaded PEGylated liposomes with D-limonene and affected percutaneous absorption by partially plugging hair follicle orifices.

This study identified key genes and pathways involved in the seasonal hair cycle regulation of yak, uncovering molecular mechanisms that may aid in understanding their adaptation to alpine environments.

This study found that TPA induces apoptosis in pig renal epithelial cells by affecting cell cycle proteins, and activated ras can prevent this process.

The study emphasizes that telomere shortening is identified as the sole cause of aging among the twelve hallmarks and suggests that increasing telomere and rDNA array length in adult stem cells might effectively reverse aging and extend lifespan.

This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.

This review discusses the molecular mechanisms and clinical applications of autologous platelet-derived products for TMJ regeneration, but reports no new clinical results.