2 citations
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April 2019 in “Pharmaceutical sciences and research” This study found that lotion containing ethanolic extract of Phyllanthus niruri promoted hair growth in rats, with the addition of 1% menthol enhancing this effect compared to the extract alone.
2 citations
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December 2017 in “Theriogenology” This study found that V-ATPase plays a role in the acidification of vas deferens fluid under the influence of testosterone in orchidectomized rats.
This study observed that applying an aqueous extract of Trichosanthes cucumerina leaves to Wistar rats promoted hair growth comparably to 2% Minoxidil, supporting its traditional use for alopecia.
1 citations
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October 2025 in “Ulusal travma dergisi” In this animal study, combined cellular therapy significantly improved diabetic wound healing, and probiotics further enhanced these effects by reducing oxidative stress, apoptosis, and inflammation while promoting vascularization and collagen organization.
1 citations
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January 2025 in “Advances in Dermatology and Allergology” In this animal study, PRF enhanced the repair of chronic wounds in rats by reducing inflammation and promoting collagen deposition and new blood vessel formation, potentially through activating the Wnt/β-catenin signaling pathway.
1 citations
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June 2022 in “Frontiers in Neuroanatomy” This study found that neonatal blocking of androgen and estrogen pathways in rats altered sex-specific expression of estrogen and androgen receptors in adult pituitary and adrenal glands, potentially influencing lifelong neuroendocrine function.
1 citations
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May 2022 in “Reproductive Endocrinology” This study found that administering conditioned media from glial cell cultures to late reproductive age rats increased uterine contractile activity, potentially supporting the use of cryopreservation in preserving its biological effects.
1 citations
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October 2021 in “Gene, cell and tissue” This study found that grape sap significantly improved hair growth and follicle health in male Wistar rats, suggesting its potential as a non-chemical treatment for hair loss.
1 citations
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October 2020 in “The Egyptian Journal of Histology” This study reported that ginseng had a superior therapeutic effect on benign prostatic hyperplasia in rats, showing nearly normal histological architecture compared to finasteride's incomplete restoration.
1 citations
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January 2004 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” This study concludes that SPARC is likely a secondary response during the hair cycle's transitional phases, indicating tissue-remodeling processes similar to those in wound repair, rather than initiating these transitions.
July 2026 in “Regenerative medicine reports .” This study concluded that nanoparticle-based delivery systems may significantly enhance wound healing and tissue regeneration in third-degree burns, though challenges like nanoparticle variability and cytotoxicity remain.
This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.
This study found that plasma-activated water significantly improved wound healing in diabetic rats compared to both atmospheric pressure cold plasma and conventional dressings.
January 2026 in “Minia Journal of Medical Research” In this study, testosterone-induced alopecia in male rats led to significant thinning and follicular degeneration, but treatment with adipose-derived stromal vascular fraction cells markedly improved these histological changes, suggesting a potential role in hair follicle regeneration.
October 2025 in “International Journal of Cell and Biomedical Science” In this study, the application of human umbilical cord mesenchymal stem cell secretome significantly increased hair follicle count in fluconazole-induced alopecia in rats, although changes in epidermal thickness were not significant, suggesting a novel approach for hair restoration.
May 2025 in “Psychopharmacology” In this study, chronic finasteride administration in male rats led to depression- and anxiety-like behaviors only in specific tests and moderately affected hippocampal synaptic plasticity, possibly due to adaptive plasma corticosterone level changes over time.
April 2025 in “Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )” In this study, researchers observed that Cuscuta reflexa extract mitigated inflammation and oxidative stress in testosterone-induced benign prostatic hypertrophy in Wistar rats, suggesting its potential as an adjunctive therapy for BPH.
January 2025 in “International Journal of Veterinary Science” In this animal study, hibiscus leaf simplicia ointment was found to protect red blood cell levels and promote better hair growth in UV-exposed rats, though it did not maintain normal skin histology; the ointment showed no significant acute dermal toxicity.
December 2024 in “Majalah kedokteran Bandung/Majalah Kedokteran Bandung” In this study, carrot seed oil applied at a 75% concentration increased hair root, shaft, and tip thickness in rats, but did not promote hair length growth.
October 2024 in “International Journal of Pharmaceutics” This study found that a topical formulation with nanostructured lipid carriers containing finasteride significantly restored hair follicles in androgenetic alopecia-induced rats without systemic absorption, suggesting its potential for safer and effective AGA treatment.
July 2024 in “Behavioural Brain Research” In this study, male Wistar rats with obesity showed reduced depressive-like behaviors, brain inflammation, and oxidative stress after long-term finasteride treatment, suggesting potential benefits of finasteride in obese conditions, while lean rats experienced adverse effects including metabolic disturbances and depressive-like behaviors.
July 2024 in “Drug and Chemical Toxicology” Moringa oleifera leaf extract protects skin from damage caused by sodium valproate.
March 2024 in “Journal of Neuroscience Research” In this study, researchers found that repeated finasteride administration in female rats led to antidepressant- and anxiolytic-like effects, potentially linked to increased estradiol and decreased corticosterone levels, with implications for neurosteroid-based treatments in women.
January 2024 in “Reproductive toxicology” This study found that hesperidin, a bioflavonoid, mitigated the negative effects of finasteride on sperm health and testicular structure in male Wistar rats by reducing oxidative stress and apoptosis and supporting testicular antioxidant capacity.
January 2024 in “Journal of Applied Health Sciences and Medicine” In this study, Nephrolepis biserrata extract significantly improved fertility indices in male Wistar rats with testosterone propionate-induced benign prostatic hyperplasia, showing increased sperm count and reduced prostate weight, suggesting potential pro-fertility benefits for BPH-related infertility.
November 2023 in “European heart journal” In this study, finasteride improved cardiac sympathovagal balance in aging and obese male rats, also enhancing left ventricular function specifically in those modeled for aging, but not affecting healthy rats.
July 2023 in “International Journal of Endocrinology” In this study, researchers observed that Centratherum anthelminticum seed extract effectively reduced cholesterol, triglycerides, insulin resistance, and inflammatory markers, while normalizing hormone levels and oxidative stress markers in rodents with PCOS, suggesting potential benefits for managing the condition.
June 2023 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” In this study, researchers found that high doses of rosemary extract given to lactating mother rats adversely affected their offspring, causing weight issues and damage to liver, kidney, and testis tissues, suggesting potential teratogenic risks if used during human pregnancy and lactation.
May 2023 in “Current Applied Science and Technology” In this animal study, researchers found that exposure to a CO2 laser at various power levels caused significant skin damage in rats, including severe burns, coagulation, and tissue obliteration, with higher laser doses resulting in more pronounced injuries.
May 2023 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” In this study, young albino rats whose mothers received high doses of rosemary extract during lactation showed negative health effects, including inhibited weight gain and organ damage, suggesting potential teratogenicity of rosemary extract when used in such conditions.