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DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Cell aging can be both good and bad for tissue repair.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

Patients on dabrafenib and trametinib for melanoma often experience skin side effects.

Cancer treatments can cause various eye problems, so eye doctors should know how to diagnose and treat these early.

MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

Scalp melanoma, a deadly skin cancer, is often found late due to its hard-to-see location, especially in older men. Early detection, possible treatments, and the role of hairdressers in spotting it early are discussed. More research is needed to improve detection and treatment.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Found different proteins in balding and non-balding cells, giving insight into hair loss causes.

Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

The combination treatment showed a higher response rate but no significant survival benefits.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.