56 citations
,
March 2015 in “Cell death and differentiation” This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.
28 citations
,
December 2006 in “Clinical lung cancer” This review outlines various non-rash skin toxicities associated with novel targeted anticancer therapies and provides guidelines for their early diagnosis and management, but reports no new clinical results.
22 citations
,
September 1993 in “Archives of Dermatology” This case report details a 4-year-old girl who developed a fever and widespread papular, pruritic rash resembling a heat rash, with a progression to thick, scaly patches but had sterile blood and urine cultures.
10 citations
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January 2018 in “Functional Foods in Health and Disease” This study found that berry extracts, especially black raspberry extract, may have anti-aging effects due to their high antioxidant activities.
10 citations
,
January 1985 in “PubMed” This study observed that hair zinc concentration in normal infants decreased from birth to eight months before rising again at twelve months, with lower levels associated with hair loss and diaper rash.
6 citations
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September 1988 in “Drug intelligence & clinical pharmacy” This report documents a case of dermatological toxicity associated with chronic minoxidil therapy, highlighting the emergence of a severe rash after three years of use, which recurred upon inadvertent rechallenge.
5 citations
,
July 2017 in “Skin appendage disorders” This case report describes a 35-year-old man who developed an atypical DRESS syndrome after taking topiramate for migraine prevention, which resolved with drug withdrawal and symptomatic treatment.
4 citations
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October 2013 in “PLoS ONE” This study found that Vemurafenib led to a broad range of cutaneous side effects in nearly all patients with advanced melanoma, highlighting the need for regular dermatologic management and UV protection.
1 citations
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November 2020 in “International Journal of Dermatology” In this case report, the authors suggest that methotrexate-induced rheumatoid papular eruption is a rare side effect of methotrexate, resolved after discontinuation, which may be linked to rheumatic conditions.
January 2005 in “Enlighten: Publications (The University of Glasgow)” In this transgenic mouse study, preliminary findings suggest that overt melanocyte hyperplasia may require prior keratinocyte hyperplasia, indicating a potential role for keratinocyte mutation in early melanoma development.
January 2026 in “Journal of Ayurveda and Integrated Medical Sciences” In this case report, a multimodal Ayurvedic treatment combining Gunjadi Taila, Rasayana therapy, and Prachhanna Karma successfully reduced hair fall, scalp itching, dandruff, and dryness in a 32-year-old male, suggesting its effectiveness for managing these scalp disorders.
January 2026 in “International Journal of Rheumatic Diseases” This study explored the intersection of art and medicine, specifically examining the depiction of the malar rash associated with lupus in historical paintings. The authors suggest that this approach, known as iconodiagnosis, can enhance medical education and understanding of disease manifestations through visual arts.
July 2025 in “International Journal of Ayurvedic Medicine” In this pilot study, Kantavallabha rasa, an Ayurvedic medicine, showed significant improvements in PCOS symptoms such as menstrual irregularities, pain, unwanted hair growth, skin issues, and ovarian conditions among 10 women with PCOS.
June 2023 in “International journal of research in ayurveda and pharmacy” This study explores how Dhatryadi rasayana, a polyherbal formulation with antioxidant properties, may help prevent and treat premature hair greying by addressing factors such as oxidative stress, nutritional deficiencies, and hormone imbalances, potentially through rasayana therapy.
January 2023 in “IP International Journal of Comprehensive and Advanced Pharmacology” This review discusses immunomodulatory formulations to address post-COVID conditions and reports no new clinical findings.
June 2017 in “The Medical Journal of Australia” This article provides no abstract or new research findings.
September 2015 in “Pediatrics in review” The 7-month-old boy has a persistent rash that doesn't improve with typical skin treatments.
November 2014 in “The Pediatric Infectious Disease Journal” This case study of a 3-and-a-half-year-old girl with skin lesions revealed a diagnosis of extensive suppurative folliculitis with mixed granulomatous reaction upon further examination of hair follicles.
136 citations
,
March 1998 in “Oncogene” This study found that transgenic mice overexpressing E2F1 in their epidermis developed skin tumors, confirming in vivo that deregulated E2F1 activity can contribute to tumor development.
10 citations
,
September 1997 in “Molecular carcinogenesis” This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.
4 citations
,
January 2009 in “Acta agriculturae Serbica” This study observed that both excessive and deficient selenium levels in a C57BL/6 mouse model were associated with hair loss and changes in hair follicles, likely due to alterations in the hair follicle cycle and increased apoptosis.
1 citations
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October 2023 in “International Journal of Ayurvedic Medicine” This article discusses the potential benefits of decade-wise Rasayana therapy in enhancing female reproductive health by addressing various life stages, from pre-menarche to post-menopause, and draws from traditional and contemporary sources to conceptualize its importance.
This review highlights concerns about dermatological side effects linked to rapid weight loss from glucagon-like peptide-1 receptor agonists used for type 2 diabetes and obesity treatment, such as skin laxity, decreased collagen, and hair loss, emphasizing the importance of managing these while retaining metabolic benefits.
July 2022 in “Journal of Investigative Dermatology” This study found that the KrasG12D mutation alters ERK signal dynamics in hair follicle stem cells, leading to tissue deformation, and suggests a collective effect of mutant cells is necessary for disruption.
December 2023 in “Revista de la Facultad de Ciencias Médicas (Quito)” This case report describes a 15-year-old female whose initial systemic lupus erythematosus manifestations were fever and rash appearing separately, illustrating diagnostic challenges between SLE and infection.
July 2023 in “The Journal of Family Practice” This case study describes a 29-year-old man who presented with a fever and a generalized maculopapular rash, alongside symptoms like hair loss and joint pain, leading to an investigation into whether his condition was a case of the "great masquerader.
June 2023 in “British Journal of Dermatology” This study reviews historical accounts suggesting several British monarchs suffered from various skin diseases, including leprosy, psoriasis, stasis dermatitis, systemic lupus erythematosus, and porphyria.
March 2018 in “The journal of applied laboratory medicine” This article presents a case study of a 3-month-old boy with a worsening rash initially diagnosed as impetigo, which did not improve with antibiotics and required further dermatological investigation.
February 2016 in “Journal of Allergy and Clinical Immunology” This report highlights a case of disseminated and recurrent infundibulofolliculitis in a 45-year-old African American male and underscores the importance of performing a skin biopsy for diagnosis.
September 2015 in “Pediatrics in review” This case study reports that a 7-month-old boy's diffuse rash and hair loss were attributed to zinc deficiency and resolved with zinc supplementation.