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Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Liquid nitrogen spray caused a temporary, harmless swelling under the skin in an elderly woman.

All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

New acne treatments show promise as alternatives to traditional therapies.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

Minoxidil and retinol together help hair grow.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.