research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
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research Hair Follicle Regeneration in Skin Grafts: Current Concepts and Future Perspectives
Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
research The Dynamic Duo: Niche and Stem Cell Interdependency
Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
research Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Chemotherapy-Induced Hair Loss: The Use of Biomarkers for Predicting Alopecic Severity and Treatment Efficacy
Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.
research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
research Epithelial Skin Biology: Stem Cells and Epidermal Homeostasis
The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Valproic Acid Promotes Human Hair Growth in In Vitro Culture Model
Valproic acid may help hair grow and could be a safe treatment for hair loss.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Aging in Hair Follicle Stem Cells and Niche Microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research CC-Type Glutaredoxins Mediate Plant Response and Signaling Under Nitrate Starvation in Arabidopsis
ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.
research Advances in Understanding Hair Growth
Understanding glycans and enzymes that alter them is key to controlling hair growth.
research Biochemistry of Epidermal Stem Cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Emerging Therapies for Acne Vulgaris
New acne treatments show promise as alternatives to traditional therapies.
research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Interventional and Intrinsic Airway Homeostasis and Repair
The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.
research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research The Hair Follicle as a Dynamic Mini-Organ
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells
miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.
research Wnt Signaling and Aging-Related Heart Disorders
Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Altered Hair Root Gene Expression Profiles Highlight Calcium Signaling and Lipid Metabolism Pathways Associated With Curly Hair Initiation and Maintenance in Mangalitza Pigs
Genes related to calcium signaling and lipid metabolism are important for curly hair in Mangalitza pigs.
research Human Hair Follicle: An Update on Biology and Perspectives in Hair Growth Disorders Treatment
New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research Epithelial Stem Cells: Turning Over New Leaves
Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
research Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.