research Raynaud Phenomenon - Reply
Doctors disagree on whether Raynaud phenomenon often leads to serious diseases, but agree that patients should be monitored for possible progression while being reassured. Rapid weight loss may cause hair loss.
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research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Diseases of the Skin: Drug Ill Effects on the Skin
All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.
research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells
Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
research Rapid Determination of Finasteride in Human Plasma by UPLC-MS/MS and Its Application to Clinical Pharmacokinetic Study
New method measures finasteride in blood quickly and accurately.
research Finasteride
Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
research Trends in Nanotechnology for Practical Applications
Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.
research Microneedle Arrays Combined With Nanomedicine Approaches for Transdermal Delivery of Therapeutics
Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
research Development and Optimization of Finasteride-Cinnamon Oil-Loaded Ethanol-Free Microemulsions for Transdermal Delivery
The optimized microemulsion with cinnamon oil effectively delivers finasteride through the skin without damaging hair.
research Alopecia Types, Current and Future Treatment
Current alopecia treatments manage symptoms but don't cure, and better treatments are needed.
research Lecithin Organogels as a Potential Phospholipid-Structured System for Topical Drug Delivery: A Review
Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Vitamin D Receptor: New Assignments for an Already Busy Receptor
The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Polymeric Nanoparticles-Based Topical Delivery Systems for the Treatment of Dermatological Diseases
Polymeric nanoparticles show promise for treating skin diseases.
research Oral Minoxidil in Trichology: A Review
Oral minoxidil helps with hair growth but needs more research to fully understand its effectiveness and safety.
research Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
Ketoconazole increases finasteride's effectiveness and lifespan in the body.
research Microneedles in the Clinic: A Comprehensive Review of Clinical Studies and Applications
Microneedles are being used and tested for various medical and cosmetic treatments.
research PC040: Amalgam Tattoo of the Oral Mucosa
Finasteride may cause gum problems, but stopping the drug can improve these issues.
research Topical Application of Cyclosporin A Induces Rapid Remodeling of Damaged Anagen Hair Follicles in Cyclophosphamide-Administered Mice
Cyclosporin A helps damaged hair follicles regrow hair quickly.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research MicroRNAs in Skin Tissue Engineering
MicroRNAs could improve skin tissue engineering by regulating cells and changing the skin's bioactive environment.
research Fabrication and In Vitro Evaluation of Silk Fibroin-Folic Acid Decorated Paclitaxel and Hydroxyurea Nanostructured Lipid Carriers for Targeting Ovarian Cancer Cells: A Double Sword Approach
The new drug carriers show promise for better targeting and treating ovarian cancer.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.