This study found that inhibiting mTORC2 in glioblastoma cells reduced DNA repair and increased apoptosis, highlighting its potential role in cancer cell survival and DNA damage response.
102 citations
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October 2010 in “Molecular Pharmaceutics” In this study, copper-doxorubicin liposomes with multidose therapy reduced systemic toxicity compared to ammonium sulfate-loaded doxorubicin liposomes, while combinatorial strategies further enhanced tumor regression and accumulation.
11 citations
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June 2023 in “Journal of Cellular Biochemistry” This study suggests that BRAF inhibitors, particularly Encorafenib and Dabrafenib, may have potential applications in wound healing by targeting specific proteins involved in the healing process in murine models.
This study discovered that in *Drosophila*, knockdown of specific storage proteins in adipocytes decreased germline stem cell maintenance, implicating a role for these proteins in adult tissue regulation.
In this study, Sox13 was identified as a novel marker for early hair follicle development and differentiation in mice, though it appears to be dispensable for overall epidermal and adnexal development.
1 citations
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January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that hypothyroidism in women with PCOS significantly increased insulin resistance and obesity, which might worsen metabolic issues and impact conditions like hair loss and infertility.
21 citations
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May 2024 in “American Journal of Medical Genetics Part A” This study observed that among patients with Myhre syndrome, those with the SMAD4 gene variant p.Arg496Cys experienced fewer symptoms like hearing loss, while those with the p.Ile500Thr variant often had severe aortic hypoplasia, highlighting the diverse symptom progression and genetic factors of this rare condition.
May 2023 in “Journal of Drugs in Dermatology” This study reported that the novel topical serum REVIVV®, containing a blend of phytochemicals, significantly improved hair growth and reduced shedding in 150 participants with androgenetic alopecia after 8 weeks of use, while also being rated easy to use and prompting plans for continued use.
November 2020 in “Journal of The American Academy of Dermatology” Oral health affects overall well-being, with tooth loss impacting quality of life, nutrition, and health.
187 citations
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June 1999 in “Journal of The American Academy of Dermatology” This study reported that finasteride 1 mg/day significantly increased hair growth and slowed hair loss in men with frontal scalp hair thinning over one year, and these benefits continued or improved in the second year.
10 citations
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July 2013 in “British Journal of Dermatology” High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.
31 citations
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January 2019 in “Journal of Cutaneous Medicine and Surgery” This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.
12 citations
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January 2021 in “Springer eBooks”
11 citations
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May 2021 in “Dermatologic clinics” This review discusses platelet-rich plasma and cell-based therapies for hair loss, noting promising results but emphasizing the need for standardization and robust trials to confirm their efficacy.
6 citations
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April 2004 in “Dermatologic Surgery” This study found that 32% of men continued finasteride use for 1 to 3 years, with many reporting poor hair growth results.
2 citations
,
January 2021
1 citations
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June 2023 in “Journal of Cosmetic Dermatology” This study found that while clinical evidence is limited, early preclinical results suggest exosome treatment may enhance hair growth and warrant further research for therapeutic use in alopecia.
1 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that platelet-rich plasma treatment increased hair density and reduced inflammation in patients with patchy alopecia areata, but not in a patient with alopecia universalis.
1 citations
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January 2020 in “Skinmed” This review discusses the potential of exosome therapy for treating androgenetic alopecia but reports no new clinical results, highlighting the need for trials to confirm its efficacy and safety.
April 2026 in “Dermatologic Clinics”
December 2024 in “Journal of Cosmetic Dermatology” This study found that exosomes derived from platelet-rich plasma show preclinical promise for wound healing but lack sufficient data for other dermatological uses like hair growth and skin rejuvenation.
This review concluded that the efficacy of cosmeceutical hair serums for addressing hair loss lies in their use of bioactive peptides and plant compounds, like flavonoids and sterols, that target eight key contributing factors identified in hair loss conditions.
May 2004 in “Dermatologic Surgery” In this study, 32% of men continued taking finasteride for androgenetic alopecia after 1 to 3 years, but only a small percentage reported hair growth.
March 2023 in “Advances in Cosmetic Surgery” This review discusses the potential of exosomes as a therapy for hair loss and the need for better regulation and understanding of their molecular effects, but reports no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that academic stress, family history, and lifestyle factors are significantly associated with hair loss among pharmacy students and faculty in a private college in Telangana, India.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that hair loss among students and faculty at a private pharmacy college in Telangana, India, was significantly associated with academic stress, family history, and lifestyle factors.
July 2012 in “Ubaya Repository (University of Surabaya)” This study found that hair growth gel and tonic containing red grape seed extract were physically and chemically unstable under high temperature and humidity conditions over 30 days.
In this study, researchers observed that dysregulated innate lymphoid cells type 1, alongside CD8+ T cells, may contribute to the pathogenesis of alopecia areata by affecting hair follicle health.
January 2019 in “Georg Thieme Verlag eBooks” This review suggests that platelet-rich plasma therapy shows promise for androgenetic alopecia and may be effective for some alopecia areata and cicatricial alopecia cases, but more robust trials are needed.
5 citations
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September 2018 in “Acta histochemica” This study observed that proteins in the mTOR signaling pathway are expressed differently in the hair follicles of patients with lichen planopilaris and frontal fibrosing alopecia, suggesting a role in the pathogenesis of these conditions.