April 2023 in “Journal of Investigative Dermatology” This review discusses randomized trials on PRP and laser therapy for vitiligo, acne scars, and skin rejuvenation, finding combination therapy may yield clinical improvements but calls for more diverse studies.
December 2025 in “Journal of lasers in medical sciences” This randomized controlled trial reported that light-emitting diode therapy significantly reduced ecchymosis and edema and accelerated wound healing in patients during the first two weeks following rhinoplasty, without any adverse effects.
67 citations
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March 2018 in “The Journal of Clinical Endocrinology & Metabolism” This study reported that estrogen-progestin oral contraceptives, antiandrogens, and insulin sensitizers are more effective than placebo in treating hirsutism in women, with combination therapies generally proving superior to monotherapy.
August 2021 in “Asian Journal of Pharmaceutical and Clinical Research” In this randomized trial, a solid shampoo formulated with plant extracts was more effective than placebo in improving androgenetic alopecia and reducing hair cortisol and DHT concentrations in men.
2 citations
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February 2009 in “Journal of Evidence-Based Medicine” This review of randomized controlled trials for alopecia areata treatments found that none were significantly better than placebo in promoting long-term hair growth, with most trials being small and poorly reported.
8 citations
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May 2025 in “Acta Obstetricia Et Gynecologica Scandinavica” This meta-analysis reported that dienogest and combined oral contraceptives had comparable efficacy and tolerability for endometriosis treatment, with therapeutic choice suggested to be based on patient preference and clinical history.
30 citations
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February 2016 in “British journal of dermatology/British journal of dermatology, Supplement” This review found moderate to very low-quality evidence that spironolactone, flutamide, and cyproterone acetate combined with oral contraceptives may reduce hirsutism more effectively than placebo or metformin, though results vary among other treatments.
30 citations
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April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
18 citations
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February 2016 in “The Journal of Clinical Endocrinology and Metabolism” This article reviews emerging opportunities and challenges in male reproductive medicine, including advancements and unmet needs in erectile dysfunction, androgen deficiency, and fertility, but reports no new clinical findings.
48 citations
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May 2012 in “Journal of Midwifery & Women's Health” This review discusses the symptoms, diagnosis, and current treatment recommendations for polycystic ovary syndrome, noting that many women may remain undiagnosed and at risk for complications.
5 citations
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January 2014 in “Current Dermatology Reports” This review discusses various treatments for adult acne in women, including topical, systemic, and alternative therapies, and reports no new clinical results.
August 2024 in “Journal of Cosmetic Dermatology” This study explored the effectiveness of injectable treatments for androgenetic alopecia, finding that dutasteride and growth factor formulations achieved clinically significant results compared to controls like saline and topical minoxidil, within selected trials from 2000 to 2023.
4 citations
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December 2014 in “PubMed” This review suggests that dihydrotestosterone pretreatment may improve cosmetic outcomes in hypospadias repair, but more randomized trials are needed to determine its effectiveness due to currently limited evidence.
In this study, researchers aim to evaluate the effectiveness and safety of combining plum-blossom needle tapping with ginger juice rubbing to prevent hair loss in obese women after metabolic bariatric surgery, through a randomized controlled trial involving 96 participants.
5 citations
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April 2019 in “Plastic and reconstructive surgery. Global open” This literature review suggests that fractional laser therapies may positively impact hair regrowth in androgenic alopecia, though current evidence is mostly limited to small studies and case reports, highlighting a need for more comprehensive randomized controlled trials to confirm their efficacy and safety.
April 2026 in “International Journal of Research in Dermatology” This meta-analysis found that laser-based therapies showed promising clinical benefits in treating scarring alopecias, such as disease stabilization and symptom improvement, but highlighted the need for high-quality randomized controlled trials due to serious risk of bias and methodological limitations in existing studies.
1 citations
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January 2016 in “Recenti Progressi in Medicina” This article discusses the limitations of relying on literature and regulatory documents for pharmaceutical evidence, proposing public health decisions be based on independent trials like those by the Mario Negri Institute.
February 2022 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study reviewed 44 clinical trials and found that home-based laser devices are effective for short-term hair removal and skin rejuvenation, with common side effects including erythema and edema; additional trials are needed to confirm safety and efficacy.
January 2006 in “Arquitectos: información del Consejo Superior de los Colegios de Arquitectos de España” This study found that curcumin may improve glycemic control and lipid metabolism in patients with PCOS, although its effects on low-density lipoprotein and triglycerides were not significant.
August 2024 in “Journal of Clinical Medicine” This review examines quality control in preparing platelet-rich plasma, highlighting knowledge gaps in its clinical efficacy and safety, but reports no new clinical results.
5 citations
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October 2020 in “Giornale italiano di dermatologia e venereologia” This study found that a phyto-caffeine-containing shampoo was more effective than a control shampoo in reducing hair loss and improving hair strength in women with androgenetic alopecia over a 6-month period.
July 2026 in “Journal of Cosmetic Dermatology” This network meta-analysis found that for female pattern hair loss, microneedling combined with minoxidil ranked highest for hair density and patient satisfaction, while poly-L-lactic acid threads plus minoxidil led in hair diameter; however, the evidence is uncertain and lacks placebo-controlled trials.
January 2026 in “Dermatologic Therapy” This study suggests that autologous platelet concentrates may improve inflammatory activity, disease control, and hair regrowth in primary cicatricial alopecia, but the evidence is limited by small sample sizes and study quality.
August 2017 in “Journal of biotechnology” This review found that topical corticosteroids hold the highest level of evidence as a first-line treatment for pediatric alopecia areata, but further trials are needed to explore additional therapies.
February 2021 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that women with telogen effluvium had significantly lower serum copper and zinc levels compared to controls, suggesting these deficiencies may be associated with the condition.
1 citations
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September 2021 in “Skin appendage disorders” This systematic review of five studies found that intradermal and intramuscular botulinum toxin injections showed promising hair growth outcomes for men with androgenic alopecia, but emphasizes caution due to a lack of control groups and small sample sizes.
December 2025 in “JMIR Dermatology” This study observed that patients using a novel topical combination of finasteride and minoxidil for male androgenetic alopecia reported high satisfaction and good tolerance, with few side effects and no need for higher-level care, despite limitations such as retrospective data and no control group.
June 2025 in “Journal of Cosmetic Dermatology” In this study, a shampoo and hair tonic containing the botanical extract blend Asacurin100 reduced hair loss and improved scalp health in 35 male participants with androgenetic alopecia, without serious side effects, suggesting potential efficacy that warrants larger trials for confirmation.
12 citations
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April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia” This review discusses the prenatal care guidelines for women with systemic lupus erythematosus and emphasizes the need for disease activity control to reduce maternal and fetal complications; it reports no new results.
March 2026 in “Journal of South Asian Federation of Obstetrics and Gynaecology” This study found that prophylactic administration of autologous platelet-rich plasma during cesarean wound closure significantly improved wound quality and reduced the incidence of surgical site infections.