research Alopecia Areata: An Evidence-Based Treatment Update
Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.
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research Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study
Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
research Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement
PRP shows promise but lacks consistent evidence and regulation.
research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors
Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.
research Optimal Management of Frontal Fibrosing Alopecia: A Practical Guide
Early diagnosis and combination therapy, especially with finasteride and dutasteride, are key to managing Frontal Fibrosing Alopecia effectively.
research Clinical Snippets: Dermatological Findings and Insights
A hormone affects hair growth, certain molecules may prevent skin damage, a skin disease is linked to immune cells, glycerol helps skin hydration, and psoriasis treatment trials need improvement.
research A Randomized Placebo-Controlled Multicenter Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)
Finasteride may help some male chronic pelvic pain patients, but more research needed.
research Promising Alternative Clinical Uses of Prostaglandin F2α Analogs: Beyond the Eyelashes
Prostaglandin F2α analogs show promise for treating certain types of hair loss but need more research for other skin conditions.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research Platelet-Rich Plasma for Androgenic Alopecia: A Randomized, Placebo-Controlled, Double-Blind Study and Combined Mice Model Experiment
PRP injections promote hair growth and increase hair density in androgenic alopecia.
research Minoxidil 2% Lotion for Eyebrow Enhancement: A Randomized, Double-Blind, Placebo-Controlled, Split-Face Comparative Study
Minoxidil 2% lotion is safe and effective for making eyebrows thicker and fuller.
research Preparing Regenerative Therapies for Clinical Application: Proposals for Responsible Translation
The document suggests a need for collaboration, better evidence, and a responsible framework to safely and effectively advance regenerative therapies to clinical use.
research A Spermidine-Based Nutritional Supplement Prolongs the Anagen Phase of Hair Follicles in Humans: A Randomized, Placebo-Controlled, Double-Blind Study
A spermidine-based supplement may help hair grow longer by keeping it in the growth phase.
research Efficacy and Safety of a New 5% Minoxidil Formulation in Male Androgenetic Alopecia: A Randomized, Placebo-Controlled, Double-Blind, Noninferiority Study
New 5% minoxidil formula safely and effectively treats male hair loss.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
research A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome
Finasteride improves chronic pelvic pain, saw palmetto doesn't.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
research Androgens and Hair: A Biological Paradox with Clinical Consequences
Androgens can both increase body hair and cause scalp hair loss.
research Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies
Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
research Adipose-Derived Stem/Stromal Cells in Regenerative Medicine
Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
research Efficacy and Safety of the Oral Janus Kinase Inhibitor Baricitinib in the Treatment of Adults with Alopecia Areata: Phase 2 Results from a Randomized Controlled Study
Baricitinib is effective and safe for treating severe alopecia areata.
research Musculoskeletal and Body Composition Response to High-Dose Testosterone with Finasteride After Chronic Incomplete Spinal Cord Injury: A Randomized, Double-Blind, and Placebo-Controlled Pilot Study
Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.
research Comparison of Microneedling With Platelet Rich Plasma Versus Minoxidil (5%) Plus Finasteride (0.1%) Topical Therapy in Androgenetic Alopecia: A Randomised Clinical Study
Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
research Clinical Benefits of Baricitinib Therapy for Severe Alopecia Areata
Baricitinib treatment helps regrow eyebrow, eyelash, and scalp hair in severe alopecia areata, improving patients' emotional well-being and quality of life.
research Does Topical Minoxidil at Concentrations Higher Than 5% Provide Additional Clinical Benefit?
Using more than 5% minoxidil can help hair growth more, but results vary and side effects may increase.
research Efficacy and Safety of Proxalutamide in Severe or Critically Ill COVID-19 Patients: Study Protocol for an Exploratory Trial
The trial will test if proxalutamide is safe and effective in reducing death in severe COVID-19 patients.
research The Use of Janus Kinase Inhibitors in Alopecia Areata: A Review of the Literature
JAK inhibitors show promise for treating hair loss in alopecia areata but need more clinical trials to confirm safety and effectiveness.