3 citations,
November 2021 in “Clinical, Cosmetic and Investigational Dermatology” Platelet-Rich Plasma may improve skin health and reduce wrinkles, but more research is needed for standard treatment guidelines.
August 2021 in “International Journal of Dermatology and Venereology” Platelet-Rich Fibrin (PRF) can speed up healing in chronic wounds, improve hair density, and act as a natural filler for skin rejuvenation, but its use in hair loss treatment needs more evaluation.
January 2018 in “The Journal of Urology” Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.
37 citations,
October 2021 in “Nutrients” Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
61 citations,
January 2019 in “American Journal of Clinical Dermatology” The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.
119 citations,
July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
2 citations,
September 2022 in “Frontiers in Nutrition” High-dose vitamin D3 does not improve symptoms or quality of life in COVID-19 patients after one year.
1 citations,
June 2018 in “JAMA Dermatology” Vitamin C was found to effectively treat prickly heat in children.
32 citations,
February 2017 in “Dermatologic Surgery” The evidence for using Low-Level Laser Therapy for hair loss is limited and more thorough research is needed.
4 citations,
October 2022 in “Dermatology Research and Practice” Methotrexate alone is as effective and safe as combining it with prednisolone for treating Lichen planopilaris.
3 citations,
November 2018 in “Oncology issues” Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.
5 citations,
October 2020 in “JAMA Dermatology” Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.
November 2023 in “Research Square (Research Square)” Combining calcipotriol and PRP is most effective for treating Alopecia Areata.
December 2022 in “Skin appendage disorders” The review analyzed five randomized clinical trials (RCTs) to evaluate the efficacy of combining low-level light therapy (LLLT) with topical minoxidil for treating androgenetic alopecia (AGA). The studies used wavelengths of 600–1,100 nm and treatment durations of at least 16 weeks. Results showed that combination therapy of LLLT and minoxidil (either 2% or 5%) was either superior or equivalent to minoxidil monotherapy in promoting hair regrowth. Some studies indicated that the combination therapy improved hair density more than monotherapy, especially in the early months, but this advantage diminished by the end of the study periods. Overall, the combination therapy appears to offer some early benefits over monotherapy.
August 2022 in “Journal of Investigative Dermatology” The review analyzed five randomized clinical trials (RCTs) on the efficacy of combining Low Level Light Therapy (LLLT) and topical minoxidil for treating androgenetic alopecia (AGA). The studies compared LLLT with 2% or 5% minoxidil to either no treatment, 5% minoxidil alone, or LLLT alone. Results varied, with some studies showing greater improvement in hair density and diameter with combination therapy, while others found no significant difference between combination therapy and minoxidil monotherapy. Early outcomes suggested a potential advantage of combination therapy, but this benefit diminished over time. The review concludes that more rigorous clinical trials with larger sample sizes and stratification by alopecia severity are needed to determine the true efficacy of combination therapy.
Using minoxidil daily with monthly minoxidil mesotherapy is more effective for hair loss than monthly PRP microneedling treatments.
November 2013 in “Journal of Mazandaran University of Medical Sciences” Minoxidil with caffeine works better for hair loss than minoxidil alone.
5 citations,
September 2021 in “Cureus” Depression in women with Polycystic Ovarian Syndrome (PCOS) is linked to insulin resistance and hyperandrogenism, and managing these can help reduce depression. Lifestyle changes and Cognitive Behavioral Therapy can be effective treatments.
March 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Combining nonablative fractional laser with minoxidil was effective for alopecia areata with only one patient relapsing after a year.
20 citations,
September 2019 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil effectively and safely treats patchy hair loss, but more research needed.
May 2017 in “Actas urológicas españolas” 5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.
9 citations,
May 2021 in “Archives of Dermatological Research” Home-based skin care devices are generally safe and effective for hair removal, promoting hair growth, treating wrinkles and acne, but results for psoriasis treatment are mixed.
78 citations,
January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
April 2024 in “JAMA dermatology” Oral minoxidil is as effective as topical minoxidil for male hair loss but has more side effects like excessive hair growth and headaches.
15 citations,
May 2022 in “Journal of Infection” COVID-19 vaccines are safe and highly effective for children, with inactivated vaccines being slightly better.
January 2001 in “Clinical and Experimental Dermatology” A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.
66 citations,
September 2023 in “International Journal of Andrology” Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.
39 citations,
February 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
21 citations,
September 2017 in “Journal of Obstetrics and Gynaecology Research” Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.
March 2023 in “East African scholars journal of medical sciences” Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.