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In this study, silver nanoparticles were found to penetrate porcine skin to depths ranging from 11.1 μm to 15.6 μm, potentially surpassing the stratum corneum thickness.

This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.

In this study, chemical treatments during permanent hair straightening were found to randomize proteins in the cortex, aiding in the reconnection of disulfide bonds during oxidation.

This study found that permanent waving treatment induces structural changes in the cortex proteins of white human hair, significantly reducing its tensile strength without altering the S-S band intensity.

This study demonstrates that spatially resolved IR and Raman imaging can effectively reveal the molecular structure and composition of untreated human hair, providing insights into its chemistry and structural integrity.

In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.

This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.

This preliminary study suggests that Raman micro-spectroscopy can help differentiate basal cell carcinoma from hair follicles in skin tissue sections, although some misclassification of hair follicles as carcinoma was observed.

This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.

This study found that waving virgin human hair with thioglycerol at pH 9.0 using ammonia solution caused less damage than using thioglycolic acid, while maintaining good waving efficiency.

This study found that hydrophobic amino acids from egg white hydrolyzed protein and L-phenylalanine effectively penetrate deep into the human hair fiber, increasing specific contents in both virgin and bleached hair.

In this study, the authors concluded that a hydrolyzed eggwhite protein treatment promoted the reconnection of disulfide bonds in excessively bleached hair, after reduction and oxidation processes in permanent waving.

This study observed that bleaching brown human hair with persulfate salts and hydrogen peroxide induced significant conformational changes in keratin, particularly affecting disulfide bridges and oxidized sulfur species, which may inform the development of hair restorative treatments.

This study found that hair from ovarian teratomas shares similar chemical composition and morphology with scalp hair, but differs in physical properties and cysteic acid bands.

In this study, researchers used Raman spectroscopy to identify melanin-specific features in mouse hair as potential biomarkers for gamma-radiation exposure, achieving a sensitivity of 88% and specificity of 83%, with classification accuracy declining over time beyond 7 days post-irradiation.

This study found that Raman spectroscopy has potential for detecting biophysical differences in basal cell carcinoma compared to normal skin structures, supporting its future use in Mohs surgery.

This study investigated the mechanical response of the human hair cuticle to strain and found that cuticular deformation directly corresponded with fiber elongation, revealing significant molecular-level changes in disulfide crosslinks but maintained structural stability, highlighting the role of the cuticle in stress resistance.

This study observed that the Raman spectra of human hair cuticle vary with polarization and direction of signal collection, identifying certain spectral bands as markers sensitive to the structural changes in keratin secondary and tertiary structures.

This review discusses the use of Raman spectroscopy to evaluate drug penetration in alopecia treatments and suggests it may be a promising tool for enhancing the effectiveness of laser-assisted drug delivery.

In this study, high-dose oral administration of Ramania leaf ethanol extract in Wistar rats resulted in no significant acute toxicity symptoms, though gastric ulcers and hair loss were observed. The extract is classified as non-toxic under specified guidelines, with an LD50 greater than 5000 mg/kg.

This study demonstrated that FT-Raman spectroscopy is effective for identifying finasteride polymorphs in tablets and detecting the presence of alternative polymorphs down to about 15% concentration.

In this study, Raman micro-spectroscopy did not support the hypothesis of structural changes in hair follicles due to miniaturization in women with androgenetic alopecia.

This study used confocal Raman microscopy to confirm optical similarity between human and porcine hair follicles, supporting its use in assessing trans-follicular drug delivery.

This study found that nano-sized lipid particles improved the skin accumulation and retention of dexamethasone compared to a base cream, suggesting potential benefits for inflammatory skin disease treatment.

This study found that a blend of low- and high-molecular weight hyaluronic acid significantly improved penetration into the hair cortex compared to individual HA types, reducing frizz and increasing hair elasticity and water content, as measured by Confocal Raman Spectroscopy.

This study examined the effectiveness of FT-Raman spectroscopy for detecting polymorphism in Lamivudine and Finasteride, highlighting its advantages over other methods due to its capability to provide sharp, well-resolved spectral bands and reduced sampling issues.

This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.

This study used enhanced Raman spectroscopy to successfully detect ultra-low levels of free testosterone in women with PCOS, suggesting a potential low-cost method for early diagnosis.

In this report, two adult patients with Tatton-Brown-Rahman syndrome exhibited new cardiac features, such as atrial fibrillation and ventricular and atrial dilatation, highlighting the importance of cardiovascular follow-up in adults with this condition.