July 2026 in “Organoid Research” In this review, researchers summarize key factors in constructing skin organoids, including cell source and assembly methods, and emphasize advances such as air-liquid interface culture for improving tissue development, aiming to guide standardized protocols and future clinical applications.
January 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study found that three months of using topical 5% minoxidil significantly improved hair count and shaft thickness in patients with androgenetic alopecia, highlighting its effectiveness and safety despite varied response levels among the subjects.
September 2025 in “Frontiers in Medicine” This study assessed the effectiveness of various combinations of minoxidil with other agents for androgenetic alopecia, finding that platelet-rich plasma and basic fibroblast growth factor combined with minoxidil significantly increased hair density, while different combinations were optimal depending on gender.
September 2025 in “Dermatology and Therapy” This systematic review and meta-analysis found that platelet-rich plasma (PRP) therapy is effective in increasing hair density and reducing hair loss for alopecia, with variations in response based on activation status.
This article explores how natural and man-made factors shape architecture and environments for human activity in emergency situations, focusing on the unique conditions of the Republic of Kazakhstan. Results are not reported.
This article explores how natural and man-made factors shape architecture and environments in emergency situations, focusing on principles relevant to Kazakhstan's specific conditions. Results are not reported.
This study found that PIXE microanalysis effectively detected and quantified trace element changes in hair shafts, revealing a marked decrease in copper after treatment for green hair syndrome.
March 2026 in “Journal of Aesthetic Nursing” This study suggests that neither autologous platelet-rich plasma nor 5% topical minoxidil reliably outperforms the other as a monotherapy for male androgenetic alopecia, with combination therapy often showing superior outcomes.
In this study, minoxidil combined with PRP was found to effectively increase hair density in women with female pattern hair loss, but showed no superiority over minoxidil alone. No major side effects were reported.
This study found that the patient receiving microneedling and platelet-rich plasma treatment showed earlier significant improvements and high satisfaction compared to the patient treated with microneedling and topical minoxidil.
January 2020 in “Skinmed” In this study, microneedling combined with platelet-rich plasma led to earlier improvements and high patient satisfaction in a man with androgenic alopecia, compared to microneedling with topical minoxidil.
211 citations
,
March 2011 in “Journal of Lipid Research” This study reports a novel LC/MS method that separates and analyzes all known ceramide subclasses in human stratum corneum, identifying a new subclass, CER [EOdS], with minimal sample preparation.
126 citations
,
August 2018 in “Molecular Systems Biology” This study found that in murine dermis, fibroblast state switching between proliferation and ECM deposition plays a crucial role in tissue architecture and wound healing.
98 citations
,
December 2015 in “The Journal of Cell Biology” In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.
97 citations
,
December 2021 in “Cells” This review outlines key considerations for designing fluorescence microscopy experiments in cell biology, discussing the importance of hardware availability, suitability of biological models, and imaging agents to achieve high-resolution and informative images.
54 citations
,
January 2021 in “Biophysics Reports” This review highlights the current progress and application pros and cons of various cell-based screening platforms in drug discovery, discussing challenges and potential improvements for these innovative methods.
50 citations
,
November 2021 in “Viruses” This study observed that in vitro exposure to dihydrotestosterone worsened COVID-19 spike protein-induced endothelial injury, while spironolactone showed potential in reducing this effect, suggesting a rationale for further evaluation in treating COVID-19.
49 citations
,
October 2022 in “PubMed” This review examines alopecia, its causes, the impact of micronutrients, and the role of the Mediterranean diet, noting conflicting data and a need for more research on diet's effect on hair loss.
35 citations
,
February 2023 in “Biomolecules” This review explores the role of Granzyme B in autoimmune skin diseases and highlights its potential as a therapeutic target due to its involvement in impaired barrier function and inflammation.
29 citations
,
October 2020 in “eLife” This study using Mendelian randomization in UK Biobank data suggests that lifelong increased free testosterone may have mixed effects, including increased bone density and prostate cancer risk, warranting well-powered trials to address uncertainties.
27 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the role of histone marks in the transition between quiescence and proliferation in cells, and reports no new findings, emphasizing the potential existence of a histone "code" for quiescence.
16 citations
,
September 2022 in “International Journal of Molecular Sciences” This study reported that Juniperus sabina needle extract showed significant anti-butyrylcholinesterase activity, suggesting potential medicinal value due to high podophyllotoxin levels.
16 citations
,
August 2021 in “Tumor Biology” This review discusses the dual role of the TMPRSS2 gene in coronaviral lung infection and prostate cancer, cautioning against TMPRSS2 inhibitors for early prostate cancer due to potential pro-inflammatory effects.
15 citations
,
June 2016 in “Computers in Biology and Medicine” This study's simulation found that Ascorbyl Tetraisopalmitate penetrates more efficiently through the skin's stratum corneum than via the infundibulum, following different pathways and dynamics in each membrane.
7 citations
,
June 2022 in “Biology” In this study, researchers observed that male COVID-19 patients with more than 23 CAG repeats in the androgen receptor gene and lower testosterone levels experienced more severe disease outcomes.
6 citations
,
January 2020 3 citations
,
October 2023 in “Cosmetics” This narrative review concluded that lifestyle factors such as nutrition, sleep, exercise, and social interactions play key roles in improving skin health and well-being with aging, and suggests social media campaigns could promote beneficial lifestyle changes in the future.
2 citations
,
October 2024 in “Phytochemistry Reviews” Abrus precatorius has medicinal benefits but can be toxic.
2 citations
,
August 2024 in “Heliyon” This study concluded that Metformin may be suitable for prophylaxis or mild COVID-19, while a combination of Oseltamivir, Tamoxifen, and Dexamethasone could benefit moderate to severe cases, highlighting the need for more trials on other drug candidates.
1 citations
,
April 2025 in “Journal of Clinical Medicine” This review reports that alopecia areata negatively affects sexual functioning, highlighting the need for further research due to limitations in current study sizes and populations.