January 2015 in “IP Indian journal of clinical and experimental dermatology” This study found statistically significant associations between female androgenetic alopecia and certain components of metabolic syndrome, such as increased waist circumference and hypertriglyceridemia, in the Kashmiri population.
May 2012 in “15th International & 14th European Congress of Endocrinology” Taking 1mg finasteride tablets for 6 months can lower good cholesterol (HDL) and raise triglycerides in men with hair loss.
1 citations
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February 2013 in “African Journal of Pharmacy and Pharmacology” This study found that in patients with androgenetic hair loss, taking 1 mg of finasteride daily significantly raised triglyceride levels and decreased HDL levels after 3 and 6 months.
This study found a significant association between androgenetic alopecia and metabolic syndrome, with AGA patients showing higher BMI, waist circumference, blood glucose, and cholesterol levels compared to controls.
3 citations
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August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.
2 citations
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January 2016 in “US Endocrinology” This study found that 27% of women with polycystic ovary syndrome reported perceived scalp hair thinning, which was associated with factors like advancing age, subjective hirsutism, disturbed sleep, smoking, abnormal glucose tolerance, and meal skipping.
September 2023 in “Research Square (Research Square)” In this study, overweight women with polycystic ovarian syndrome who took evening primrose oil for 10 weeks experienced significant reductions in BMI, LDL, and total cholesterol levels, alongside hormonal changes such as decreased LH, FSH, and testosterone levels, and increased estrogen.
17 citations
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January 2014 in “Journal of Clinical and Diagnostic Research” This study found that patients with oral lichen planus and oral lichenoid reactions have higher levels of serum cholesterol and LDL-C than healthy individuals, suggesting a potential elevated risk for cardiovascular disease.
177 citations
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December 2002 in “The Lancet” In this study, single fibrinogen/LDL apheresis showed a significant improvement in speech perception for patients with plasma fibrinogen concentrations over 295 mg/dL compared to standard treatment for sudden sensorineural hearing loss.
1 citations
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May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” In this study, women with androgenetic alopecia showed higher cholesterol levels and carotid artery thickness, suggesting a potential link between female AGA and cardiovascular disease.
20 citations
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June 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found that long-term dutasteride therapy in men with benign prostatic hyperplasia worsened erectile dysfunction, reduced testosterone levels, and increased blood glucose and lipid profile, indicating negative metabolic impacts.
July 2022 in “World Journal of Advanced Research and Reviews” This study found that methanolic extract of Cordia plathytyrsa increased testosterone levels in male rats but did not affect other evaluated metabolic parameters.
16 citations
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January 2018 in “International journal of trichology” This study observed that individuals with premature hair graying had lower levels of certain serum nutrients and lifestyle factors like stress and smoking may contribute; hair oiling appeared protective.
16 citations
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May 2019 in “Hormone and Metabolic Research” This systematic review found insufficient evidence to support protective effects of selenium on polycystic ovary syndrome complications, despite some studies suggesting it may reduce insulin resistance and dyslipidemia.
1 citations
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July 2022 in “Functional foods in health and disease/Journal of functional foods in health & disease” This study found that oral probiotic supplementation over 12 weeks may improve hair growth, skin condition, metabolic health, and stress responses in Chinese adults with hair loss and a high risk of metabolic syndrome.
January 2024 in “Circulation” This commentary explores the role of PCSK9 as a target for drug development, underscoring that individuals with PCSK9 loss-of-function mutations experience significantly lowered LDL cholesterol levels and reduced coronary events, suggesting that full inactivation of PCSK9 is effective and safe.
5 citations
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April 2014 in “Journal of Obstetrics and Gynaecology Research” This study found that young women with PCOS had normal thyroid function but showed alterations in lipid metabolism, which may predispose unmarried women in this group to cardiovascular diseases.
January 2014 in “S. Karger AG eBooks” Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.
January 2021 in “Menoufia Medical Journal” This study found a significant correlation between metabolic syndrome components, particularly waist circumference and hypertension, and female pattern hair loss.
October 2018 in “International Journal of Research in Dermatology” In this study, androgenetic alopecia patients had a significantly higher prevalence of metabolic syndrome and related metabolic disorders compared to those without the condition.
September 2023 in “JEADV Clinical Practice” This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.
February 2024 in “Clinical and Experimental Obstetrics & Gynecology” This study found no significant differences in fat distribution between Thai women with and without polycystic ovary syndrome, though PCOS women with abnormal glucose tolerance showed higher arm fat.
This study reported that high cholesterol levels were linked to increased prostate cancer risk, while selenium supplementation affected gene expression, suggesting nutritional and clinical factors might influence prostate cancer risk and biology.
October 2025 in “Turkish Journal of Biochemistry” This study found that patients with tropical chronic pancreatitis exhibited significantly reduced plasma amino acid levels and antioxidant capacity, with folate deficiency identified as a key factor in hyperhomocysteinemia.
September 2025 in “International Journal of Zoology and Applied Biosciences” This study found that women aged 21-26 with PCOS showed significant differences in biochemical and hormonal profiles, such as blood sugar and hormone levels, compared to healthy individuals, suggesting an increased incidence of PCOS in this age group.
7 citations
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January 2014 in “Rinshō shinkeigaku” This report describes two cases of stroke associated with finasteride use for male-pattern hair loss, suggesting a potential link to thrombosis due to increased estrone and estradiol levels.
31 citations
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February 2021 in “Nutrients” This study found that curcumin may improve glycemic control and certain aspects of lipid metabolism in patients with polycystic ovary syndrome.
4 citations
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February 2023 in “Research Reports in Clinical Cardiology” This study found that the ACE gene DD genotype and D allele are linked to an increased risk of hypertensive IHD complications, with dyslipidemia also identified as a significant risk factor for ischemic heart disease.
June 2023 in “Pharmaceuticals” This review reports that sex-related differences in pharmacological response have been observed in SARS-CoV-2 infection, dyslipidemia, and diabetes mellitus, with implications for treatment strategies; for example, men may respond better to genomic vaccines for SARS-CoV-2, while women may benefit more from certain antiviral medications.
35 citations
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August 2021 in “BMC Medical Genomics” This study found that serum metabolic profiles differ significantly between polycystic ovary syndrome patients and healthy controls, highlighting potential metabolic markers for diagnosing and prognosing PCOS.