This study determined that the incidence of Discoid Lupus Erythematosus at the Government General Hospital, Chennai, from 2006 to 2008 was 1.7 per 1000, with localized and disseminated forms manifesting distinctive demographic and clinical patterns.
This study investigated the epigenetic effects of finasteride on reproductive signaling pathways using Sertoli cell models and found that finasteride exposure led to altered epigenetic profiles in multiple genes, including ESR1 and DNMT3A, indicating potential impacts on reproductive-related pathways.
May 2022 in “Journal of Neurology Neurosurgery & Psychiatry” This case report highlights the overlap of Sjögren’s Syndrome and Systemic Lupus Erythematosus, noting major salivary gland enlargement and bilateral facial nerve involvement, which may better explain the patient's symptoms than lupus alone.
January 2025 in “International Journal of Dermatology Research” This study found that patients with alopecia areata had a significantly higher mean platelet volume compared to healthy individuals, suggesting a potential link between hematological markers and the severity of the disease.
14 citations
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January 2012 in “International Journal of Trichology” This case report highlights the importance of suspecting underlying malignancy, such as Hodgkin's lymphoma, in patients with diffuse hair loss and other cutaneous symptoms.
77 citations
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April 2004 in “Gene expression patterns” This study observed specific expression patterns of three zebrafish estrogen receptor genes during development, highlighting robust co-expression of esr2a and esr2b in primary neuromasts, branchial arches, and other tissues.
13 citations
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October 2024 in “Scientific Reports” In this study using data from young women in West Bengal, India, the researchers identified that leptin signaling impairment, insulin resistance, and specific gene mutations significantly contribute to PCOS, with obesity commonly manifesting in affected individuals.
June 2024 in “Research Square (Research Square)” This study found that among young women in West Bengal, India, co-occurring PCOS and related conditions like estrogen resistance and leptin receptor insufficiency are common, with notable genetic variations identified, including impairments in leptin signaling and insulin resistance.
April 2023 in “Research Square (Research Square)” This study found that lower GPX4 mRNA levels in polymorphonuclear neutrophils of systemic lupus erythematosus patients were negatively associated with disease activity and serological markers, suggesting a diagnostic value for GPX4 mRNA.
January 2023 in “Indian dermatology online journal” In this case report, an 8-year-old boy's crusted scalp lesions and alopecia initially mimicking kerion were ultimately diagnosed as Pre-B acute lymphocytic leukemia after histopathological evaluation revealed leukemia cutis.
3 citations
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February 2015 in “Mechanisms of development” This study observed that areola formation in mice requires exposure to pregnancy hormones and mechanical strain, beyond individual stimuli like hormonal milieu or strain alone.
2 citations
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May 2025 in “Infection” This source underscores the need for a multidisciplinary effort to raise awareness of Demodex and demodicosis, suggesting that prioritizing research, diagnostics, and treatment development could enhance global health outcomes and improve quality of life for affected individuals.
December 2023 in “Asian journal of medical sciences” This study from S.C.B. Medical College explored the clinico-etiological and histopathological patterns of erythroderma, observing psoriasis as the most common cause, followed by idiopathic cases and atopic or drug-induced dermatitis, highlighting the need for careful management and awareness of alternative medicine use.
5 citations
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January 2021 in “Daru” This case report highlights a rare instance of severe multi-organ involvement following a single dose of methotrexate for ectopic pregnancy, requiring intensive care but ultimately successfully treated with leucovorin and supportive care.
1 citations
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August 2007 in “Indian Journal of Pediatrics” This case report describes a 13-year-old girl with atypical symptoms leading to a delayed diagnosis of HIV infection with fatal disseminated cryptococcosis.
May 2025 in “The Journal of Rheumatology” This study highlights the efforts of the Oyemam Autoimmune Foundation in raising awareness and supporting lupus patients in Ghana, amid challenges like misdiagnosis and insufficient healthcare resources, revealing the impact of their advocacy and counseling initiatives on patients' lives.
April 2015 in “Andrology” This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.
This review discusses cyclosporine A's mechanisms of action and side effects compared to tacrolimus in renal transplantation, but it reports no new experimental results; the authors highlight implications for cardiovascular risk management.
April 2026 in “International Journal of Impotence Research” This review outlines the major health consequences of anabolic-androgenic steroid abuse, with a focus on sexual and reproductive issues, and suggests management prioritizes cessation and relapse prevention due to lack of robust randomized trials.
This study found that mesotherapy combined with minoxidil for androgenetic alopecia shows promise with high patient satisfaction and manageable risks, though some uncommon side effects may occur.
1 citations
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April 2022 in “Rheumatology” This case study describes a 4-year-old boy with juvenile dermatomyositis whose severe subcutaneous edema resisted conventional treatment, necessitating aggressive immunosuppression for disease control.
1 citations
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March 1999 in “British journal of rheumatology” Adequate steroid treatment needed to limit bone loss in PMR patients.
258 citations
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July 2016 in “Reproductive Biology and Endocrinology” This abstract reviews the characteristics and health risks associated with polycystic ovary syndrome and does not report new findings, highlighting the syndrome's multifactorial nature.
January 2025 in “Directory of Open access Books (OAPEN Foundation)” This book reviews the symptoms, diagnosis, and treatments for Polycystic Ovary Syndrome, providing a comprehensive exploration but reports no new clinical results.
223 citations
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September 2018 in “Rheumatology” This review examines clinical data on the efficacy and safety of JAK inhibitors used for immune-mediated conditions beyond rheumatoid arthritis, highlighting their potential therapeutic roles in various inflammatory diseases.
34 citations
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August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
9 citations
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May 2012 in “British Journal of Dermatology” This article discusses female androgenetic alopecia but reports no new clinical findings.
7 citations
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January 1993 in “Rheumatology” This article discusses suspected skin toxicity from drugs used to treat rheumatoid arthritis but reports no new clinical findings.
5 citations
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October 2014 in “Scottish medical journal” This case study reports the first known instance of isolated sub-acute cutaneous lupus erythematosus potentially induced by long-term nitrofurantoin therapy, with effective treatment using topical steroids and hydroxychloroquine.
1 citations
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July 2014 in “Nepal journal of dermatology, venereology & leprology” This study observed that chronic kidney disease patients undergoing hemodialysis frequently experience dermatologic manifestations, with xerosis and white nail being the most common skin and nail changes noted in 74% and 56% of patients, respectively.