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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Activated ras can protect kidney cells from a certain substance that causes cell death.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Phosphatidic acid may help hair grow by affecting cell growth pathways.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Using neurohormones to control keratin can lead to new skin disease treatments.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Sorafenib after liver surgery may increase survival for some liver cancer patients.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Patients on dabrafenib and trametinib for melanoma often experience skin side effects.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Sorafenib can cause delayed skin problems, so patients need careful monitoring.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Wound healing is complex and requires more research to enhance treatment methods.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Plant extracts can help prevent hair loss and promote hair growth.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Chicken feather gene mutation helps understand human hair disorders.