2 citations
,
October 2016 This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.
4 citations
,
March 1989 in “PubMed” This article discusses the side effects of radiation therapy on specific body areas and offers guidance on patient management, but it introduces no new results.
1 citations
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January 2021 in “Journal of Cancer Therapy” This article reviews regenerative medicine strategies, such as stem cells and plant polyphenols, for mitigating radiotherapy side effects but does not present new clinical findings, calling for further investigation.
This ongoing study is evaluating whether Ayurvedic treatments, specifically Panchagavya Ghrita combined with Amalakyadi Kashaya, can improve the quality of life for cancer patients experiencing side effects from chemotherapy and radiotherapy, compared to standard care, using a variety of quality-of-life and symptom severity scales.
31 citations
,
August 2022 in “Frontiers in Oncology” This review discusses the potential benefits of photobiomodulation for managing side effects of cancer therapy and provides specific guidelines for its use in supportive cancer care, without presenting new clinical results.
5 citations
,
August 2025 in “Biomedicines” This review highlights the significant impact of cutaneous and oral mucosal adverse events on patients undergoing breast cancer treatment, emphasizing the need for early detection and comprehensive management to maintain treatment adherence and enhance patient care.
3 citations
,
December 2011 in “Pediatric Dermatology” In this case report, estrogen substitution therapy slightly increased hair volume in a 22-year-old patient with genetic predisposition to hair loss and alopecia caused by past treatment for leukemia, but hair loss returned after stopping the therapy.
March 2023 in “Zdorov'â čolovìka” This article reviews how various medications, such as antihypertensives, chemotherapy, and hormonal contraceptives, are associated with negative effects on sexual desire and function but reports no new clinical results.
September 2017 in “Pure and Applied Biology” In this study, chemotherapy and radiotherapy were observed to normalize blood cell counts and improve quality of life in lung cancer patients, though some variations and localized side effects occurred.
8 citations
,
March 2022 in “Cancers” This study found that proton minibeam radiotherapy demonstrated a potential tissue-sparing effect in epidermis models by spatially confining DNA damage, suggesting reduced side effects in radiotherapy.
51 citations
,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” This review examines androgen replacement therapy in women for treating androgen deficiency symptoms and reports no new clinical results, while noting potential safety within a specific dose range.
19 citations
,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews the cutaneous reactions and characteristic skin changes associated with chemotherapy, radiation therapy, and new targeted cancer treatments, reporting no new clinical results.
April 2022 in “Anti-cancer agents in medicinal chemistry” In this literature review, researchers compiled evidence on repurposed synthetic radioprotective agents, including metformin and simvastatin, that have demonstrated potential in mitigating the side effects of radiotherapy in cancer treatment.
4 citations
,
April 2020 in “Reports of Practical Oncology & Radiotherapy” This review discusses the role of mental healthcare in managing sexual side effects of prostate cancer radiotherapy and highlights the importance of patient education and psychological support for improved quality of life.
3 citations
,
May 2016 in “International Journal of Research in Ayurveda and Pharmacy” This paper reviews the potential of Ayurvedic herbs like ginger, garlic, and turmeric to reduce the side effects of cancer therapies and enhance patient wellbeing but reports no new experimental findings.
February 2026 in “American Journal of Clinical Dermatology” This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.
2 citations
,
September 2020 in “International journal of radiology & radiation therapy” This study describes changes in scalp hair color, including rare instances of repigmentation, following volumetric modulated arc therapy for skin cancer; this potential side effect may warrant discussion during informed consent.
July 2021 in “Plastic and reconstructive surgery. Global open” This study identified specific genes involved in radiation-induced fibrosis in skin, capsule, and muscle tissues of breast cancer patients, offering insights that may help improve mitigation strategies for these side effects.
8 citations
,
September 2015 in “Radiotherapy and oncology” This article discusses the potential for scalp cooling to prevent hair loss during radiotherapy, drawing from its efficacy in chemotherapy contexts, but it provides no new experimental results.
October 2014 in “Cancer Research” This study observed that applying a GMP-grade botanical extract to the scalp increased Bcl-2 levels, potentially preventing premature hair follicle apoptosis in chemotherapy and radiotherapy-induced alopecia.
3 citations
,
June 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the clinical spectrum and pathobiology of radiotherapy-induced alopecia and reports no new research findings, highlighting potential pathways for future targeted RIA management.
22 citations
,
November 2020 in “Frontiers in Physics” This review discusses the experimental strategies and technological challenges of proton minibeam radiotherapy (pMBRT) and reports no clinical results; it highlights the potential of using a 3 GHz linear accelerator for precision therapy research.
February 2026 in “International Journal of Molecular Sciences” This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.
65 citations
,
January 2013 in “Cochrane library” This review found that infliximab, golimumab, and some forms of radiotherapy significantly improved nail psoriasis compared to controls, although they could have serious adverse effects and are not commonly used specifically for nail issues.
131 citations
,
October 2004 in “Clinical Cancer Research” This study suggests that applying topical Tempol to the scalp before whole brain radiation may protect against radiation-induced alopecia and is safe and well-tolerated.
17 citations
,
January 2010 in “International journal of trichology” This case report highlights the occurrence of radiation-induced alopecia in a patient undergoing radiotherapy for oropharyngeal carcinoma, emphasizing awareness of this potential side effect.
11 citations
,
October 2019 in “Journal of Cancer Immunology” This article discusses the role of external beam radiotherapy as a primary treatment method for cancer and reports no new clinical findings.
April 2023 in “Journal of Investigative Dermatology” This study suggests that the mTOR signaling pathway may play a role in the pathophysiology of radiation dermatitis, with expression patterns of S6K1 protein differing from those in normal and inflamed skin.
1 citations
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November 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, Makarova et al. found that topical vitamin D3 significantly delayed basal cell carcinoma development in UVR-exposed, BCC-prone mice, while oral vitamin D3 supplements did not prevent carcinogenesis, suggesting a potential role of UV-induced vitamin D3 in inhibiting tumor growth.
4 citations
,
February 2024 in “The Journal of Urology” This study reports that adding androgen deprivation therapy to salvage radiation therapy for patients with non-metastatic biochemical recurrence of prostate cancer after radical prostatectomy improves progression-free survival, particularly in those with higher post-prostatectomy PSA levels.