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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Human skin can make serotonin and melatonin.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Finasteride effectively blocks enzyme causing male pattern baldness.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Alopecia is a key indicator of thallium poisoning.

TSH is usually the only test needed to check thyroid function in primary care.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.