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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Activating autophagy in dogs with certain diseases improves their skin and hair.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Prolactin may be important for skin growth and immune function.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Social media often spreads unreliable skincare advice, leading to potential skin problems, especially in teens.

Betamethasone is more effective for hair regrowth than latanoprost but has more side effects.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.

Pediatricians should treat some hair loss types in children and refer others to a dermatologist.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.

Etretinate treatment changed hair growth patterns in many patients.

Some patients with high prolactin levels don't show symptoms because they have a form of the hormone that's less active.

Talc in street cocaine can cause immune-reactive skin nodules where injected.

Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.

Football players can get many skin conditions from their sport, which need different treatments and can be prevented with good hygiene and protection.

HIV can cause various nail and hair disorders, important for early diagnosis and treatment.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

Annexin A2 isoform 2 helps dermal papillae cells grow, affecting hair growth.

Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.

Oral zinc sulphate reduces dark hair color in mice.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Follicular mucinosis can be an early sign of aggressive mycosis fungoides.

Gingivitis may increase a hormone linked to ovarian function in women with a certain ovary condition, and treating gum disease could help manage it.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The study found that Central Centrifugal Cicatricial Alopecia mainly affects middle-aged African descent women, is linked to certain hair care practices and genetics, and often goes undiagnosed for years.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.