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Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Minoxidil might help treat acne scars by reducing collagen buildup.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.

Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

ILK is essential for skin development, pigmentation, and healing.

Inhalation therapy may repair and protect elastin in the lungs of COPD patients.

Ethylene and auxin hormones interact in complex ways that are essential for plant growth and development.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Phospholipase A2 enzymes play key roles in skin health and disease.