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Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Lyophilized platelet-rich plasma is beneficial and effective for various medical treatments, including tissue regeneration and hair regrowth.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.