Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.

This study found that both myo-inositol and metformin helped restore normal menstrual cycles in patients with PCOS, but myo-inositol appeared to be more effective in inducing pregnancy.

This article reviews the role of R-spondins and their receptors in bone development and metabolism, highlighting their potential modulatory effects and clinical implications for treating bone loss diseases, but reports no new clinical results.

This study reported that exogenous R-spondin-1 can restore hair follicle neogenesis in adult mouse cells, highlighting differences in gene expression and signaling pathways between fetal and adult dermal papilla cells.

This study found that overexpression of R-spondin 3 in a mice model impaired hair morphogenesis and regeneration by reducing hair matrix progenitor cell proliferation, thus disrupting the Wnt pathway's regulation of stem cells.

This study found that watercress extract may help treat hair loss by increasing RSPO1 secretion and decreasing DKK1 secretion, improving hair thickness and density in clinical trials.

In this study, researchers found that transverse sections of alopecia areata lesions showed significantly more terminal hair follicles with perifollicular lymphocytic infiltrate compared to longitudinal sections, and this immune infiltration positively correlated with the positive hair pull test in patients.

This study found that intralesional vitamin D3 injections significantly improved hair regrowth in adults with patchy alopecia areata, as measured by a 5-point semiquantitative regrowth score and dermoscopic assessment, suggesting it may be an effective and affordable treatment.

This article reviews R-Spondin-1's complex role in various skin conditions, emphasizing its diagnostic, prognostic, and potential therapeutic applications.

Finasteride effectively treats hair loss and prostate issues by blocking a specific enzyme.

In this study, a subcutaneous injection of recombinant RSPO1 was found to activate hair follicle stem cells and enhance hair regeneration in mice by stimulating the Wnt/β-catenin signaling pathway, suggesting its potential as a treatment for hair loss.

This study reported that a new deep learning algorithm using Mask R-CNN improved hair follicle classification accuracy by 4 to 15%, suggesting potential clinical application for enhanced hair loss diagnosis.

This study will explore whether combination therapy with either dutasteride or finasteride and an α1 blocker is more effective than monotherapy for treating BPH, but it reports no new results.

This study found that women with diffuse alopecia exhibited deficiencies in several trace elements, including sulfur, iron, and potassium, while men showed deficiencies in calcium, sulfur, and zinc.

This review discusses the Ayurvedic perspectives on Bhallataka, noting its detoxified forms may have various therapeutic properties, but reports no new clinical findings.

This article discusses the various skin side effects associated with targeted cancer therapies like tyrosine kinase inhibitors and EGF-R inhibitors but provides no new clinical findings.

This review discusses valproic acid as a common antiseizure medication associated with alopecia and highlights the need for its inclusion in relevant medical guides, without presenting new clinical findings.

This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.

This study demonstrates the use of rPanglaoDB, an R package for combining public single-cell datasets, to create the first unbiased transcriptome profile of fibrocytes, revealing their role in tissue healing.

In this study, TGFβR I was more highly expressed in alpaca ear skin than in back skin, suggesting it may inhibit coat hair growth, with let-7b downregulating TGFβR I protein through transcriptional repression.

This study found that XP-endo Finisher R was approximately twice as effective as passive ultrasonic irrigation in removing root filling material from curved mesiobuccal canals of maxillary molars.

Human hair keratin has a 40% α-helix structure that changes to a random coil in 8 M urea.

In a reported case, the use of ZD1839 (Iressa), an EGFR tyrosine kinase inhibitor, resulted in hair changes and acneiform eruptions as cutaneous side effects.

This study used R-language data mining to analyze patents of topical Chinese medicine for hair loss, identifying key medication patterns and ingredients in traditional formulations.

This review discusses the concept and treatment of diffuse hair loss, known as Intithār al-Sha‘r, in the Unani system, drawing from classical Unani literature without reporting new clinical results.

This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.

This study found that topical 5% aqueous extract of Trichosanthes dioica R. leaves significantly promoted hair growth in rats compared to both a control and minoxidil treatment.

In this randomized open-label clinical trial, researchers found that regular application of Bhringarajadi Taila significantly improved hair fall and scalp condition in patients with Khalitya (alopecia), with 62.5% of participants experiencing moderate to remarkable improvement after 30 days of treatment.

This study reviewed Ayurvedic texts and concepts related to hair loss, known as Indralupta, its pathogenesis involving vitiated doshas and blood, and Ayurvedic treatment approaches, highlighting its differentiation from khalitya, where hair loss is more gradual.

In this clinical study, 15 patients with osteoporosis treated with the Ayurvedic formulation Asthiposhtika Vati showed improvements in symptoms, suggesting its effectiveness in managing the condition.