Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses recent developments in α1-adrenoceptor antagonists and 5α-reductase inhibitors for treating benign prostatic hyperplasia, reporting no new clinical results while identifying potential areas for future drug development.

This study reported that compounds isolated from Alpinia zerumbet significantly promoted hair cell growth and exhibited anticancer activity in cell cultures, suggesting potential as treatments for alopecia and cancer.

This study found that forming solid dispersions and inclusion complexes of finasteride significantly increased its solubility compared to its pure form.

This study developed an efficient method for converting polymeric procyanidins into high-purity oligomeric procyanidins using a semisynthetic approach combined with separation techniques.

This study found that activating the Nrf2 pathway in human mast cells effectively suppresses degranulation and inflammation induced by substance P.

This case report suggests that anidulafungin may be associated with hair loss, highlighting the need for physicians to monitor this potential adverse effect.

This study found no increased frequency of the TNF2 allele in Mexican patients with adverse cutaneous drug reactions mediated by delayed hypersensitivity, suggesting its lower relevance compared to findings in Caucasian populations.

This study suggests that certain Dibenzo derivatives may be promising candidates for prostate cancer treatment due to their potential interactions with the androgen receptor and 5α-reductase enzyme.

This study found that cephalanthine inhibited the growth of gastric cancer cells in vitro and in vivo by inducing oxidative stress and altering energy metabolism, suggesting its potential as a treatment for gastric cancer.

This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.

This review discusses the emergence and impact of eosinophilia-myalgia syndrome related to L-tryptophan and offers insights into environmental factors affecting sclerodermatous conditions, with no new research findings presented.

This study analyzed the affinity, stability, and pharmacokinetics of compounds from Sansevieria trifasciata, reporting that three compounds showed promising molecular docking results against the androgen receptor and satisfactory pharmacokinetic profiles, similar to minoxidil, in an in-silico setting.

In this in vitro study, niacinamide was found not to stimulate VEGF synthesis across a wide range of doses.

This review focused on the bioactive compounds and pharmacological properties of Lawsonia inermis (henna) and found that it contains various beneficial compounds with potential therapeutic applications, such as antioxidant and anti-inflammatory effects, indicating a need for further investigation into its medical benefits.

This review covers hair dye formulations, their mechanisms, and potential applications, but reports no new findings; the authors highlight the process of oxidative dyeing and repairing damaged hair.

This article examines the potential of using oral minoxidil as an adjuvant treatment for patients with severe alopecia areata who do not respond to increased doses of Janus kinase inhibitors, but provides no new clinical results.

This study validated a new RP-HPLC method for accurately determining doxazosin mesylate and finasteride in bulk powders and capsule formulations.

This study discovered that the disposition of LY191704 enantiomers in rats and dogs is both stereoselective and species specific.

This study reviewed various studies and concluded that Janus kinase inhibitors, particularly tofacitinib, seem to promote hair regrowth in about half of patients with alopecia areata, though expected class-specific adverse effects were observed.

In this case report, a domestic shorthair cat with Trypanosoma evansi infection fully recovered after treatment with diminazene aceturate and supportive therapies, with no Trypanosoma detected in the blood following the treatment course.

This study established a new reverse-phase high-performance liquid chromatography method to accurately and precisely quantify silodosin and dutasteride in mixtures, meeting International Council of Harmonization validation criteria for stability, sensitivity, and recovery.

This review of Lawsonia inermis L., or henna, details its bioactive compounds and historical uses in Unani medicine, including treatment for various conditions like ulcers and jaundice, while highlighting its potential for wound healing, hepatoprotective, and other effects, though further research is needed.

This study reviewed the current analytical techniques for estimating finasteride, a drug used for treating benign prostatic hyperplasia, acute urine retention, and male pattern hair loss.

This research reported that the FDA approved Litfulo® (ritlecitinib) as the first oral treatment for severe alopecia areata in adolescents over 12 years old, with 23% of treated patients showing significant hair regrowth in clinical trials compared to 1.6% with placebo.

This study evaluated the effectiveness and safety of a cinchonine nanostructured lipid carrier serum for hair growth in mouse models, finding that it significantly increased hair length and enhanced follicle penetration compared to controls, with no notable irritation observed.

This article reviews the classification and treatment of cutaneous manifestations in systemic lupus erythematosus, highlighting the importance of monitoring for disease progression and reports no new clinical results.

This review summarizes the chemical composition and pharmacological properties of Teak (Tectona grandis) but presents no new research findings, emphasizing its use in traditional medicine and therapeutic potentials.

This study developed a validated HPLC method for accurately estimating dutasteride and its related compounds in capsules, suitable for routine and stability sample analysis.

This study found that the ethanolic extract of Guazuma ulmifolia, or mutamba, showed only intermediate levels of phenolic compounds and low antioxidant activity in laboratory tests, suggesting limited potential in alleviating oxidative stress conditions like cancer or cardiovascular diseases.

The study reported that both ethanol and water extracts of pakis munding roots significantly promoted hair growth in male rabbits, showing better results than the marketed hair growth drug minoxidil.