This animal study found that YH0618 may alleviate doxorubicin-induced alopecia and affects proteins like keratin and Smad3, suggesting potential therapeutic targets. The researchers analyzed protein expression changes to understand YH0618's effects in treating chemotherapy-related hair loss.
June 2023 in “Aesthetic Plastic Surgery” This study introduces the PRECISE scale, a quantitative tool to classify androgenetic alopecia, aiming to improve planning and outcomes for hair transplantation surgeries by evaluating the whole hairless and thinning areas.
April 2023 in “Journal of Investigative Dermatology” This study developed a new quantitative method to measure skin cell turnover in just 4 days, showing it can effectively differentiate skincare product performance and revealing that turnover slows with age but responds more to treatments as people get older.
This study used quantitative methods to identify new geometric and mechanical parameters of curly and kinky/coily hair, aiming to improve classification and develop better personal care products for these hair types.
April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
This study found that some white or grey hairs can naturally regain pigmentation, suggesting hair greying may be reversible in certain conditions linked to psychological stress.
January 2018 in “Surgical and Cosmetic Dermatology” In this study, researchers validated a software-based method that quantitatively assesses the effectiveness of treatments for hair loss by calculating the area of hair loss using contrast in standardized photographs, proving effective for both early and advanced cases of androgenetic alopecia and telogen effluvium.
March 2015 in “Journal of Visualized Experiments” This study developed a simple and reliable technique to quantify hair loss in mice, potentially enhancing assessment and comparison of new alopecia therapies in preclinical research.
In this study, the average force required to pluck hair was significantly lower in malnourished adults, especially those with kwashiorkor, compared to well-nourished individuals.
17 citations
,
October 1981 in “American Journal of Clinical Nutrition” This study found that individuals with protein-calorie malnutrition, especially those with kwashiorkor, required significantly less force to pluck hair compared to well-nourished patients.
December 2025 in “The Oncologist” In this qualitative study, researchers found that patients with metastatic pancreatic cancer frequently experience symptoms such as tiredness, nausea, and pain, as well as impacts like anxiety, leading to a revised conceptual model to improve patient-reported outcome measures in future clinical trials.
May 2024 in “Reproductive BioMedicine Online” This systematic review found that interactions between patients with polycystic ovary syndrome and healthcare professionals often face challenges due to insufficient information sharing, inadequate patient support, and health system barriers.
48 citations
,
May 2019 in “Genome Biology” This study identified genetic, biological, and technical factors that influence circRNA expression in the human brain, connecting these factors to potential genetic risk for diseases like schizophrenia and type II diabetes.
40 citations
,
July 2013 in “Skin Pharmacology and Physiology” This study reports that among men, skin surface hydration and pH change with age, but transepidermal water loss and sebum production show less variation.
16 citations
,
February 2014 in “Journal of Investigative Dermatology” This study developed a mouse model to monitor hair follicle cycling macroscopically through live bioluminescence imaging, enabling detailed analysis of hair cycle and propagation dynamics influenced by environmental factors.
10 citations
,
January 1980 in “Ultrastructural pathology” This study suggests that elevated copper levels in domestic tapwater, exacerbated by its aggressive properties, likely contribute to green hair by damaging the cuticle and increasing copper uptake.
2 citations
,
February 2023 in “International journal of molecular sciences” This study explored a multidimensional approach to examine body hairs' physico-chemical properties, potentially supporting their use over scalp hairs in forensic and intoxication studies.
January 2026 in “British Journal of Health Psychology” This review highlights the significant impact of alopecia on personal identity and social interactions, emphasizing the need for personalized, non-pharmacological interventions and improved collaboration in healthcare training to better support those with appearance-altering conditions.
December 2024 in “Tissue and Cell” In this study, researchers developed a method to automatically detect androgen receptor nuclear translocation in dermal papilla cells using fluorescence markers and image analysis, finding that the receptor's nuclear signal peaks about 20 minutes after DHT exposure.
January 2024 in “International Journal of Biological and Environmental Investigations” This study developed and validated a reliable RP-HPLC method for accurately quantifying dutasteride in pharmaceutical formulations and bulk pharmaceuticals using a Shiseido C18 analytical column, demonstrating precision, accuracy, and sensitivity across a concentration range of 10 to 22 ppm.
January 2019 in “Data Archiving and Networked Services (DANS)” This review discusses various approaches to skin tissue engineering and the evaluation of skin substitutes, highlighting the need for more objective assessments and improved understanding of skin regeneration.
April 2018 in “Journal of Investigative Dermatology” In laboratory models of human skin, this study found that treating with resveratrol significantly increased glutathione levels, potentially enhancing the skin's antioxidant defenses.
March 2018 in “Vìsnik farmacìï” This study identified flavonoids and phytosterols in a medicated cosmetic cream developed for androgenic alopecia and proposed methods for their identification and quantification.
78 citations
,
March 1989 in “The Journal of Clinical Endocrinology & Metabolism” High-dose androgen therapy can help manage certain types of androgen resistance.
9 citations
,
November 2022 in “JAAD International” This study found that patients with alopecia areata face challenges like medical uncertainty and lack of information, highlighting the need for reliable and accessible treatment information that aligns with their preferences.
January 2026 in “Spectrum Research Repository (Concordia University)” In this systematic meta-synthesis, the researchers observed substantial variation in how individuals with alopecia manage identity and appearance changes, highlighting difficulties with acceptance, social influences, and unmet treatment needs, thus emphasizing personalized support through non-pharmacological interventions.
June 2024 in “British Journal of Dermatology” In this study, researchers analyzed internet and social media content related to hair loss, finding widespread misinformation about its causes and treatments, including unfounded criticisms of conventional therapies and promotion of alternative remedies.
30 citations
,
September 2020 in “Journal of Patient-Reported Outcomes” This study found that alopecia areata significantly impacts emotional and psychological well-being, relationships, and lifestyles, highlighting the need for increased awareness and effective treatments.
20 citations
,
August 2015 in “Behaviour change” This study identified six belief themes that may contribute to hairpulling behavior in women with trichotillomania, suggesting an important role for cognitions in this disorder's phenomenology.
20 citations
,
December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications” Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.