June 2020 in “Journal of Investigative Dermatology” Getting insurance to cover the hair loss treatment tofacitinib is hard because it's not officially approved for that use.
688 citations,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
61 citations,
April 2012 in “British Journal of Dermatology” Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
36 citations,
January 1998 in “Journal of Dermatological Treatment” The questionnaire effectively measures men's perceived hair growth and can distinguish between different treatments and dosages.
15 citations,
October 2016 in “Steroids” Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
7 citations,
January 1987 in “Archives of Dermatology” Most people using minoxidil for hair loss probably won't see significant improvement.
4 citations,
April 2016 in “Experimental Dermatology” AGA causes hair loss through follicle miniaturization and hair cycle changes; regrowth depends on anagen initiation in kenogen follicles.
1 citations,
May 2019 in “Journal of The European Academy of Dermatology and Venereology” New method, hair distribution width (HDW), improves accuracy in diagnosing androgenetic alopecia (AGA).
March 2024 in “International Journal of Clinical Pharmacokinetics and Medical Sciences” Herbal hair serums offer multiple hair and skin benefits and are becoming more popular.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Cosmetic procedures can harm hair, but damage can be minimized with knowledge and care; however, once hair is damaged, it cannot be reliably repaired.
April 2012 in “Informa Healthcare eBooks” Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.
330 citations,
December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
78 citations,
September 2006 in “International Journal of Cosmetic Science” Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
76 citations,
June 2015 in “Journal of biomedical science” Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
66 citations,
January 2000 in “Dermatology” Dandruff is a common, winter-worsened scalp condition linked to inflammation and microorganisms, treatable with products like ketoconazole, and may affect hair loss.
61 citations,
May 2007 in “Journal of Pharmaceutical Sciences” Different forms of hair loss drug can improve effectiveness.
53 citations,
September 2011 Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.
43 citations,
August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
35 citations,
March 2014 in “British Journal of Dermatology” Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
31 citations,
April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
30 citations,
January 2014 in “Dermatologic Clinics” Tight hairstyles, especially on chemically treated hair, can cause reversible hair loss if caught early but may become permanent if not addressed.
26 citations,
March 2014 in “Rheumatology” Some drugs used to treat inflammation may cause hair loss.
24 citations,
November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.
22 citations,
January 2015 in “The Cochrane library” DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
21 citations,
January 2015 in “Oncology Research and Treatment” Scalp cooling can prevent hair loss in 65% of chemotherapy patients, especially effective in breast cancer patients and certain chemotherapy types.
13 citations,
April 2019 in “Seizure” Valproic acid increases the risk of hair loss more than other drugs, especially in migraine patients, and lamotrigine may be a safer alternative.
12 citations,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
12 citations,
October 2017 in “Radiation Research” mTORC1 signaling needed for quick hair follicle recovery after radiation damage.