1 citations
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August 2023 in “Expert opinion on drug delivery” This study found that cedrol-loaded dissolvable microneedles efficiently delivered cedrol to the deep dermis, effectively promoting hair growth in C57BL/6 mice, suggesting a promising strategy for treating hair loss.
1 citations
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December 2020 in “Journal of Chemical and Petroleum Engineering” The researchers in this experimental study developed a thermodynamic model using the Peng-Robinson equation of state to optimize gas antisolvent system conditions for controlling finasteride particle size, aiming to reduce experimental trials and precisely identify precipitation pressures across different temperatures.
2 citations
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July 2020 in “Journal of Drug Delivery Science and Technology” In this study, forming inclusion complexes of Finasteride and poly (ethylene glycol) resulted in significantly improved solubility and dissolution rates, suggesting a promising new solid form for enhanced drug release.
May 2023 in “Journal of Pharmaceutical Innovation” July 2025 in “Journal of Drug Delivery Science and Technology” Hydrogel microneedles with special nanoparticles and growth factor improve hair growth better than minoxidil for hair loss treatment.
54 citations
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May 2021 in “Chemical Engineering Journal” This study found that a novel hybrid bilayer scaffold system enhanced wound healing in an in-vivo model by promoting cell viability, migration, and preventing infection, showing potential as an advanced dressing for cutaneous wounds.
37 citations
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February 2009 in “Bioorganic & Medicinal Chemistry” This study suggests that true binary and ternary inclusion complexes were formed between finasteride and 2-hydroxypropyl-ß-cyclodextrin, with or without the addition of specific polymers.
34 citations
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September 2019 in “ACS Biomaterials Science & Engineering” In this study, probiotic-functionalized nanocomposite scaffolds accelerated wound healing and inhibited harmful bacteria in burn wounds on mice, suggesting a potential new approach for infection control and healing promotion.
4 citations
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April 2022 in “Microorganisms” In this study, clinically used preoperative skin preparations with povidone iodine and chlorhexidine gluconate did not meet FDA log-reduction standards for bacterial bioburden in a porcine model, suggesting persistent infection risks.
3 citations
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July 2019 in “International journal of scientific research in science and technology” This study found that a herbal gel containing fenugreek seed extract significantly promoted hair growth on mice after 30 days of topical application.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
1 citations
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January 2019 This article discusses various treatments for alopecia, including allopathic, homeopathic, and Ayurvedic methods, as well as the traditional use of certain herbs, but reports no new clinical results.
1 citations
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August 2024 in “Polymers” This study observed that dissolving microneedles made from PVP-K90 and HPMC E50, incorporating Oryza sativa L. extract complex, showed enhanced transfollicular skin penetration and maintained safety for keratinocytes, with the P25H5 formulation demonstrating faster dissolution and greater effectiveness.
October 2023 in “Journal of Drug Delivery and Therapeutics” This study evaluated niosome-based gels for delivering salicylic acid topically to treat acne vulgaris and found that the formulation SANG5, using Carbopol 940 and nutmeg oil, demonstrated the best drug release profile.
October 2023 in “Applied materials today” In this study, researchers developed a novel TA-encapsulated microneedle applicator that successfully promoted hair growth and reduced inflammation in a C3H/HeJ mouse model of alopecia areata, potentially offering an improved alternative to existing treatments.
September 2023 in “Pharmaceutics” In this study, the authors developed a medicated face mask using electrospun fibers to deliver the active compound Eflornithine hydrochloride for managing hirsutism. The mask showed promising drug release characteristics, a high safety profile, and reduced hair growth in mice.
This review discusses how nanotechnology can potentially enhance the treatment and delivery of clomiphene citrate for ovulatory disorders, with a focus on improving solubility and minimizing side effects in women experiencing anovulatory infertility, highlighting its 80% efficacy in triggering ovulation in treated cases.
May 2015 in “Journal of The American Academy of Dermatology” Povidone-iodine nail solution effectively treats nail infections caused by chemotherapy.
April 2017 in “The Journal of Urology” This study found that patients with BPH who received finasteride before TURP experienced reduced intraoperative blood loss and improved quality of life one month after surgery compared to those who did not.
20 citations
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September 2018 in “Journal of cutaneous pathology” This study found that adnexal acantholysis does not reliably distinguish pemphigus vulgaris from pemphigus foliaceus, but the level of acantholysis and degree of dyskeratosis serve as distinguishing features among acantholytic disorders.
8 citations
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January 1977 in “Acta Haematologica” This study found that the PVP protocol, combining Peptichemio, vincristine, and 6-methylprednisolone, resulted in remission for diffuse non-Hodgkin's lymphomas with moderate side effects.
18 citations
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February 2025 in “Drug Delivery and Translational Research” This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.
2 citations
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October 2023 in “JURNAL ILMU KEFARMASIAN INDONESIA” In this study, researchers formulated a nanosuspension of kenikir leaf extract that meets physical criteria and exhibits cytotoxic activity against MCF-7 breast cancer cells.
December 2020 in “Macromolecular Symposia” This study found that incorporating acrylic and methacrylic acid into poly(N-vinyl-2-pyrrolidone) copolymers improves film mechanical properties but negatively affects their interaction with keratin for hair care applications.
21 citations
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January 2023 in “Biomaterials Science” This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.
2 citations
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September 2012 in “Pharmaceutical patent analyst” This editorial reviews recent European legal developments related to patents on second medical uses and dosage regimes, with no new research findings reported.
101 citations
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October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.
43 citations
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September 2001 in “Scanning” Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
April 2025 in “International Journal for Research in Applied Science and Engineering Technology” This study found that an herbal hair gel formulated with natural ingredients like aloe vera and essential oils showed stability, effectiveness, and aesthetic appeal, suggesting it could be a viable, safe alternative to synthetic hair gels, with potential for future production and clinical evaluation.
April 2016 in “Journal of Urology and Nephrology Open Access” This abstract discusses treatment options for benign prostatic hyperplasia and provides no new clinical results.