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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Platelet-rich plasma treatment could potentially be an effective way to treat chronic alopecia areata with minimal side effects.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Treating cystoid macular oedema in uveitis is difficult and risky.

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Polyamines help fix DNA damage accurately in cells.

Intense pulsed light (IPL) is an efficient and safe method for hair removal, reducing hair by about 80%.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Dermoscopy effectively distinguishes between acute total hair loss and other types of female hair loss.

Oral medication is necessary to treat scalp fungus in children, with griseofulvin being the usual choice.

To treat tinea capitis in children, oral antifungal medication is necessary, with newer drugs offering shorter treatment times than the traditional griseofulvin.

Early diagnosis and treatment of TPP can prevent complications.

Minoxidil may cause heart issues in animals and humans.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.