January 2026 in “Open Veterinary Journal” This study found that supplementing cat and dog food with PUFA-rich oil improved hair flexibility, brightness, and skin condition, though it also increased serum triglyceride levels, suggesting careful consideration of dosage and fatty acid composition is warranted.
137 citations
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December 2007 in “Journal of bone and mineral research” This study suggests that 1,25-dihydroxyvitamin D(3) and fibroblast growth factor 23 form a crucial axis in regulating phosphate balance, akin to its role in calcium regulation, and explores novel VDR interactions including with curcumin.
53 citations
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January 2017 in “BioMed research international” This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.
28 citations
,
January 2018 in “Biochemical Society Transactions” This review explores the role of fatty acids and bioactive lipid mediators in skin health and suggests targeting this metabolic network to control inflammation and improve skin conditions, but it reports no new findings.
19 citations
,
November 2018 in “Nutrients” This study reports that polyphenols from Annurca apples may safely promote hair growth and protect against chemotherapy-induced alopecia without interfering with chemotherapy regimens.
5 citations
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January 2003 in “Oilseeds and fats, crops and lipids/OCL. Oilseeds & fats crops and lipids” This review discusses the effects of dietary protein and its components on cholesterol, essential fatty acids, and possible health consequences, but presents no new clinical findings.
4 citations
,
April 2022 in “Animals” This study found that environmental conditions significantly influenced rabbit coat quality, while dietary linseed oil supplementation changed the fatty acid profile but did not improve coat thickness or heat protection.
3 citations
,
March 2016 in “Experimental Dermatology” This study found that a hypomorphic mutation in the Hr gene contributes to the development of diet-induced pruritic atopic skin in mice, particularly when combined with dietary deficiencies of polyunsaturated fatty acids and starch.
2 citations
,
January 2020 in “BioMed Research International” This study found that Phaeodactylum tricornutum extract enhanced hair follicle cell proliferation, indicated by increased keratin and ERK1/2 signaling, suggesting its potential for hair care applications.
1 citations
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August 2025 in “Seeds” This review examines the potential of Cucurbitaceae seeds, such as those from watermelon, melon, and pumpkin, as sustainable and innovative ingredients in cosmetics, highlighting their rich bioactive composition and benefits for skin and hair, despite challenges like environmental instability and low permeability.
April 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, supplementing adult Bichon Frises with 600 mg/kg Omega-3 PUFAs significantly improved their skin health, hair quality, feeding behavior, and metabolic health, compared to a control diet, over six weeks.
In this study, six types of cold-pressed oils commonly found in the Polish market were analyzed for their health-promoting compounds and antioxidant activity, revealing them as valuable sources of bioactive compounds like polyunsaturated fatty acids, tocopherols, sterols, and polyphenols, without exceeding recommended deterioration parameters.
May 2023 in “Pharma innovation” This review discusses PUFA-rich oil seeds and microencapsulation techniques but reports no new clinical results; the authors highlight microencapsulation as a promising method to protect PUFAs from oxidation.
July 2021 in “Journal of scientific research and reports” This review discusses the diverse health benefits of Omega-3, including cardiovascular improvements, anti-inflammatory effects, and potential benefits for joint and skin health, but reports no new clinical results.
September 2016 in “Journal of Dermatological Science” This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.
January 2015 in “Seoul National University Open Repository (Seoul National University)” This study reports that polyunsaturated fatty acids, particularly arachidonic acid alone and combined with eicosapentaenoic acid, may stimulate hair growth and enhance hair growth factors in mice and human dermal cells.
March 2014 in “CRC Press eBooks” Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that TLR2 is crucial for maintaining hair follicle health and regeneration, and its stimulation by the metabolite CEP may promote hair growth, while decreases in TLR2 and CEP in aging and obesity may hinder hair growth.
January 2020 in “Veterinary world/Veterinary World” This study found that a topical solution of essential oils, plant-extracted polyunsaturated fatty acids, and Vitamin E improved hair shine, reduced flaking and hair loss, and enhanced skin hydration in rabbits with skin issues.
August 2018 in “Journal of Investigative Dermatology” This study found that the application of polyunsaturated fatty acids, particularly arachidonic acid, promoted hair growth and anagen induction in both human dermal papilla cells and mouse models.
138 citations
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.
April 2012 in “The Journal of Urology” This case-control study found that men with earlier onset androgenetic alopecia, particularly frontal balding, may have an increased risk of prostate cancer in a multiethnic veterans cohort.
1 citations
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June 2019 in “Food Research” In this study, tempeh oil rich in PUFAs, particularly from black soybean, significantly down-regulated MMP-9 gene expression in UVB-irradiated mice skin, indicating potential for use in preventing skin photoaging.
This study found that TLR2 and its ligand CEP are crucial for maintaining hair follicle health and stimulating hair growth, with deficiencies observed in aging and obesity potentially reducing regeneration.
June 2022 in “Research Square (Research Square)” In this study, higher DHA/omega-6 fatty acid ratios were linked to increased social impairment in individuals with autism, alongside lower antioxidant enzyme levels and higher markers of lipid peroxidation.
29 citations
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January 2016 in “Annals of dermatology/Annals of Dermatology” This study found that arachidonic acid may promote hair growth by enhancing dermal papilla cell function and stimulating the anagen phase in C57BL/6 mice.
18 citations
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August 2014 in “Lipids” This study found that unsaturated fatty acids are more abundant in the cortex of human hair than on its surface, and steryl glycoside-like lipids may help bind the cuticle to the cortex.
18 citations
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June 1998 in “Circulation” This letter discusses how outdated measurement technology may obscure evidence of essential fatty acid deficiency in low-fat diet patients, potentially leading to undiagnosed EFA insufficiencies related to heart disease.
4 citations
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August 2023 in “Italian Journal of Food Science” This study found that pretreatment combining maceration with press-shear force and moist heat significantly increased the total phenolic and flavonoid contents in galactagogue herbs like banana inflorescences and Thai ginger.
September 2021 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” This study found that an ethanolic extract from the microalga Tetrathelmis tetrathele exhibited anti-inflammatory effects, promoted the proliferation of certain skin and hair cells, and inhibited 5α-reductase activity, suggesting its potential as a therapeutic agent for preventing alopecia and enhancing scalp health.