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Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.

Babies who gain weight quickly, especially in the first 3 months, may start puberty earlier.

Low selenium intake may delay puberty in boys but not in girls.

Severe acne in a young girl may indicate underlying hormonal issues.

Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.

Diagnosing both systemic lupus and hemoglobinopathy is challenging due to overlapping symptoms.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Certain maturity signs appear before and after the first release of sperm in boys.

Girls with PCOS often start puberty earlier and have signs of insulin resistance from a young age.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

A 46-year-old man showed symptoms of a rare condition usually seen in postmenopausal women, highlighting the need for dentist-dermatologist collaboration.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

A Chinese man with KID syndrome had a new mutation in the GJB2 gene.

Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.

A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.

A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.

A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

The document concludes that common menstrual disorders affect adolescent women, with the normal menstrual cycle lasting 21 to 35 days.

A woman with lupus had blood cell destruction, treated successfully with medication.

Micrografts and minigrafts for hair restoration provide high patient satisfaction and can cover large areas of hair loss, including sideburns, eyebrows, and beards.

A teenager's hair with alternating white and dark bands, known as Pili annulati, is a genetic condition that is usually harmless and often considered attractive.

Mother and son diagnosed with a rare genetic hair loss condition with no effective treatment.